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We conducted a retrospective cohort study of thromboprophylaxis rates and the quality of anticoagulation control among patients with atrial fibrillation (AF) using a large, geographically diverse database of electronic medical records. The study population consisted of 13,709 AF patients treated in US outpatient physician practices. Approximately two-thirds(More)
The objective of this study was to estimate the direct medical cost of Alzheimer disease (AD) and related dementia to the Georgia Medicaid program. A retrospective, cross-sectional, matched control group design was used. AD cases 50 years of age and older were identified by using International Classification of Diseases (9th edition, Clinical Modification)(More)
Although state Medicaid programs may bear a large portion of the costs of Alzheimer's disease (AD), current information on spending is not available. Using a health insurance claims database for a 10% random sample of California Medicaid ("Medi-Cal") recipients 60+ years of age, the authors estimated the excess cost of AD to Medi-Cal in 1995 as the(More)
We used the 2002 Healthcare Cost and Utilization Project Nationwide Inpatient Sample to assess hospital length of stay (LOS) and cost among adults with a principal diagnosis of intracerebral hemorrhage (n = 13,239). Sixty-nine percent of patients were aged > or =65 years, and 31% died during hospitalization. Mean LOS (cost) was 7.7 days (15,256 dollars)(More)
The aim of this study was to assess the cost-effectiveness of topiramate vs. no preventive treatment in the UK. Model inputs included baseline migraine frequency, treatment discontinuation and response, preventive and acute medical cost per attack [2005 GBP ( pound)] and gain in health utility. Outcomes included monthly migraines averted, acute and(More)
High and rising cancer treatment costs have forced a discussion about the use of cost-effectiveness analyses and other approaches to assess the value of cancer care. Oncologists have traditionally resisted using economic considerations in day-to-day medical considerations, though unavoidably their decisions have important resource implications, and(More)
e11121 Background: To better understand burden of illness in women with HER2+ metastatic breast cancer (MBC), we conducted a survey to evaluate their treatment experiences. METHODS This one-time, web-based survey was conducted with the help of 4 independent U.S. breast cancer support groups. Respondents were invited to participate via email, and were(More)
6613 Background: Acute myeloid leukemia (AML) is the most common type of leukemia among adults in the U.S. However, data on treatment patterns and costs of AML are sparse. METHODS Using the linked SEER-Medicare database, we retrospectively evaluated mortality, patterns of treatment, healthcare resource use, and Medicare payments associated with AML and(More)
e14584 Background: Although incidence of hepatocellular carcinoma (HCC) is increasing in the US, the economic impact of HCC has not been extensively studied. The objective of this study was to assess the burden of HCC in terms of mortality and medical care costs, relative to a control group of non-HCC Medicare patients. METHODS This retrospective analysis(More)