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Cellular and humoral inflammatory response after laparoscopic and conventional colorectal resections
Postoperative cell-mediated immunity was better preserved after laparoscopic than after conventional colorectal resection, especially in patients with malignant disease. Expand
Prognosis Factors in Carcinoma of the Head of the Pancreas
Prognosis factors in the treatment of pancreatic cancer were tumor size (T1), tumor resection and R0 status. Expand
The Impact of Laparoscopy with Carbon Dioxide versus Helium on Immunologic Function and Tumor Growth in a Rat Model
The insufflation of CO2 promotes tumor growth compared to the helium and control groups in a rat model and was associated with a significant increase in IL-10 and a decrease in TNFα plasma levels. Expand
New Therapeutic Strategies to Avoid Intra- and Extraperitoneal Metastases during Laparoscopy: Results of a Tumor Model in the Rat
Heparin slightly inhibits intraperitoneal tumor growth in vivo, while povidone iodine and taurolidine cause a significant decrease in tumor cell growth in vitro as well as intraperitonal tumor Growth in vivo. Expand
Effects of Celebrex and Zyflo on BOP-Induced Pancreatic Cancer in Syrian Hamsters
Incidence and size of macroscopic pancreatic carcinomas were decreased by single therapy with Zyflo as well as combined therapy (Zyflo + Celebrex). Expand
Does Dietary α-Linolenic Acid Promote Liver Metastases in Pancreatic Carcinoma Initiated by BOP in Syrian Hamster?
Dietary ALA increases liver metastases in BOP-initiated pancreatic cancer in the Syrian golden hamster, with significant differences in mean body weight and pancreas weight. Expand
Effects of Octreotide on Liver Metastasis and Intrametastatic Lipid Peroxidation in Experimental Pancreatic Cancer
Octreotide decreases the number and size of liver metastases in chemically induced pancreatic cancer in Syrian hamsters, and possible mechanisms are the prevention of high lipid peroxidation in non-metastatic liver as well as the increase in intrametastatic lipid per oxidation, leading to loss of integrity of spread tumor cells. Expand
Immunologic Changes during Minimally Invasive Surgery
Further clinical prospective randomized studies with relevant clinical endpoints and additional investigations of immunologic parameters are needed to prove the consequences of either minimally invasive surgery or open procedures on postoperative immune functions. Expand
Influence of Octreotide and Tamoxifen on Tumor Growth and Liver Metastasis in N-Nitrosobis(2-oxopropyl)amine-Induced Pancreatic Cancer in Syrian Hamsters
Octreotide alone and the combined therapy (octreotide/tamoxifen) decreased the incidence of macroscopic pancreatic carcinomas as well as the number and size of liver metastases and there was no difference between the tamoxifens and the control group. Expand
Endoscopic Surgery: Fit for Malignancy?
Neither experimental nor clinical data confirm the repeatedly published opinion that video-endoscopic surgery promotes tumor growth or the occurrence of implantation metastases in cancer patients. OnExpand