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Advanced oxidation protein products as a novel marker of oxidative stress in uremia.
The measurement of AOPP is proposed as a reliable marker to estimate the degree of oxidant-mediated protein damage in uremic patients and to predict the potential efficacy of therapeutic strategies aimed at reducing such an oxidative stress.
Glutathione antioxidant system as a marker of oxidative stress in chronic renal failure.
Late referral to maintenance dialysis: detrimental consequences.
Clinical and laboratory features of 65 patients who had been referred less than 1 month prior to first dialysis (late referral) and of 153 patients whoHad been previously followed-up by us for more than 6 months (early referral, or ER group) were similar in the two groups.
Elevated circulating levels of interleukin-6 in patients with chronic renal failure.
- A. Herbelin, P. Ureña, A. Nguyen, J. Zingraff, B. Descamps-Latscha
- Biology, MedicineKidney international
- 1 May 1991
Plasma IL-6 activity was significantly increased in patients with chronic renal failure and that of tumor necrosis factor alpha in both long-term and not yet dialyzed uremic patients, and a close correlation existed between the biological activity ofIL-6 and its immunoreactive level.
Serum erythropoietin and erythropoiesis in primary and secondary hyperparathyroidism: effect of parathyroidectomy.
Investigation of possible effects of PTx on serum immunoreactive erythropoietin (iEPO) in secondary and primary hyperparathyroidism patients, and in 3 patients undergoing cervicotomy for thyroid mass removal, concluded that PTx led to a striking increase of serum iEPO and blood reticulocytes in uremic patients with secondary hyperparathiroidism.
Short- and long-term efficacy of total parathyroidectomy with immediate autografting compared with subtotal parathyroidectomy in hemodialysis patients.
- E. Gagné, P. Ureña, T. Drüeke
- Medicine, BiologyJournal of the American Society of Nephrology…
- 1 October 1992
Although excellent short-term results were obtained with both procedures, satisfactory long-term control of parathyroid gland function was achieved in only one third of the patients, the other two third remaining either hypoparathyroid or developing recurrent hyperparathyroidism.
[(99m)Tc]-sestamibi parathyroid scintigraphy in chronic haemodialysis patients: static and dynamic explorations.
- I. Olaizola, J. Zingraff, P. Ambrosoni
- Medicine, BiologyNephrology, dialysis, transplantation : official…
- 1 August 2000
Because of its relatively low sensitivity the [(99m)Tc]-sestamibi scan is of limited help in the exploration of uraemic patients with severe secondary hyperparathyroidism before a first surgical PTx, but it is very useful in locating the remaining parathyroid gland in case of reoperation.
Aluminum localization in bone from hemodialyzed patients: relationship to matrix mineralization.
It is concluded that in bone from uremic patients on regular dialysis, aluminum can induce a particular form of osteomalacia, resistant to the vitamin D active derivatives, which is involved in the development of the aluminum-induced mineralization defect.
Influence of uremia and hemodialysis on circulating interleukin-1 and tumor necrosis factor alpha.
- A. Herbelin, A. Nguyen, J. Zingraff, P. Ureña, B. Descamps-Latscha
- Medicine, BiologyKidney international
The concomitant presence of IL-1 and TNF alpha in the plasma of long-term HD patients could be responsible for some of the clinical features observed in these patients, and provides strong evidence favoring the concept that HD can be assimilated to a recurrent acute-phase inflammatory response.