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Ancient human genome sequence of an extinct Palaeo-Eskimo
TLDR
This genome sequence of an ancient human obtained from ∼4,000-year-old permafrost-preserved hair provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit.
The sequence and de novo assembly of the giant panda genome
TLDR
Using next-generation sequencing technology alone, a draft sequence of the giant panda genome is generated and assembled, indicating that its bamboo diet might be more dependent on its gut microbiome than its own genetic composition.
The sequence and de novo assembly of the giant panda genome
TLDR
This corrects the article to show that the Higgs boson genome is a “spatially aggregating ‘spatiotemporal ’ organisation’, rather than a ‘cell-based’ organisation, which is more closely related to the immune system.
Purification of the Saccharomyces cerevisiae Cleavage/Polyadenylation Factor I
TLDR
The purification of CF I and its separation into two components, CF IA and CF IB, are described, indicating that RNA14 and RNA15 proteins exist in a tight complex.
Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor
TLDR
The aim was to identify and clone blocking mAbs from the memory B cell repertoire of recently recovered CO VID-19 patients to prevent the entry of COVID-19 virus to the host cells.
Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor
TLDR
Two monoclonal antibodies cloned from memory B cells of patients recently recovered from COVID-19 are reported, and both mAbs specifically bind to the spike (S) protein of SARS-CoV-2 and effectively neutralize S protein-pseudotyped virus infection.
Extracellular Signal-regulated Kinase (ERK) Regulates Cortactin Ubiquitination and Degradation in Lung Epithelial Cells*
TLDR
Evidence is provided that lipopolysaccharide-induced cortactin degradation is mediated by extracellular regulated signal kinase (ERK), which provides evidence that LPS modulation of Cortactin stability is coordinately regulated by stress kinases and the ubiquitin-proteasomal network.
The Genetic Architecture of Gene Expression in Peripheral Blood.
Anesthesia Management and Perioperative Infection Control in Patients With the Novel Coronavirus
TLDR
A protocolized approach that uses diagnostic criteria to clearly define benchmarks from the medical history along with clinical symptoms and laboratory tests is presented that direct the choice of protective materials and/or techniques for personal protection and prevention of cross-contamination.
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