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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere. Expand
Genome-wide identification of polycomb-associated RNAs by RIP-seq.
A RIP-seq method is developed to capture thePRC2 transcriptome and identify a genome-wide pool of >9000 PRC2-interacting RNAs in embryonic stem cells, some of which may be used as biomarkers and therapeutic targets for human disease. Expand
Activation of the Indole-3-Acetic Acid–Amido Synthetase GH3-8 Suppresses Expansin Expression and Promotes Salicylate- and Jasmonate-Independent Basal Immunity in Rice[W]
Overexpression of GH3-8 results in enhanced disease resistance to the rice pathogen Xanthomonas oryzae pv oryzAE and abnormal development may be caused by inhibition of the expression of expansins via suppressed auxin signaling. Expand
Activation of p53 by MEG3 Non-coding RNA*
It is found that transfection of expression constructs for MEG3 and its isoforms results in a significant increase in p53 protein levels and dramatically stimulates p 53-dependent transcription from a p53-responsive promoter, supporting the concept that M EG3 functions as a non-coding RNA. Expand
CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain
It is demonstrated that, in the adult mouse forebrain, immunoreactivity for a neural stem cell marker, prominin-1/CD133, is exclusively localized to the ependyma, although not all ependymal cells are CD133+. Expand
Responses of streamflow to changes in climate and land use/cover in the Loess Plateau, China
[1] To control the severe soil erosion in the Loess Plateau, China, a great number of soil conservation measures including terracing, afforestation, and construction of sediment-trapping dams haveExpand
An introduction to InP-based generic integration technology
The paper explains the concept of generic photonic integration technology using the technology developed by the COBRA research institute of TU Eindhoven as an example, and it describes the current status and prospects of generic InP-based integration technology. Expand
Mitochondrial dynamics regulates migration and invasion of breast cancer cells
A marked upregulation of mitochondrial fission protein dynamin-related protein 1 (Drp1) expression is found in human invasive breast carcinoma and metastases to lymph nodes and treatment with a mitochondrial uncoupling agent or adenosine triphosphate synthesis inhibitor reduced lamellipodia formation and decreased breast cancer cell migration and invasion. Expand
Valproate Administered after Traumatic Brain Injury Provides Neuroprotection and Improves Cognitive Function in Rats
The findings indicate that valproate given soon after TBI can be neuroprotective, and support the further testing ofvalproate as an acute therapeutic strategy. Expand
Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol.
The results suggest that the endogenous CSE/H(2)S pathway contributes to the pathogenesis of isoproterenol-induced myocardial injury, at least by its direct scavenging of oxygen-free radicals and reducing the accumulation of lipid peroxidations. Expand