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A novel cell cycle-associated lncRNA, HOXA11-AS, is transcribed from the 5-prime end of the HOXA transcript and is a biomarker of progression in glioma.
The comprehensive lncRNA expression signature in glioma has not yet been fully elucidated. We performed a high-throughput microarray to detect the ncRNA expression profiles of 220 human gliomaExpand
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Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth
Glioblastoma stem cells (GSCs) are implicated in tumor neovascularization, invasiveness, and therapeutic resistance. To illuminate mechanisms governing these hallmark features, we developed a de novoExpand
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Interleukin-6, but not C-reactive protein, predicts the occurrence of cardiovascular events after drug-eluting stent for unstable angina.
BACKGROUND Evidences concerning the predictive value of baseline inflammatory biomarkers after drug-eluting stent (DES) placement are controversial, mainly because the use of statin was not preciselyExpand
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MicroRNA-940 inhibits glioma cells proliferation and cell cycle progression by targeting CKS1.
  • H. Luo, R. Xu, +7 authors Y. You
  • Biology, Medicine
  • American journal of translational research
  • 15 August 2019
Glioblastoma (GBM) is the most frequently occurred malignant human tumor that arise in brain with a poor prognosis. microRNAs (miRNAs) are vital small molecules during GBM initiation and progression.Expand
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Prediction of clinical outcomes in patients with unprotected left main trifurcation lesions treated by drug-eluting stents: importance of 2-stent technique and SYNTAX score.
BACKGROUND There were insufficient data on the prognosis of stenting for patients with trifurcated unprotected left main lesions (UPLMS). METHODS From the SPEED (stents for percutaneous treatmentExpand
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MiR-181b suppress glioblastoma multiforme growth through inhibition of SP1-mediated glucose metabolism
Background Glucose metabolic reprogramming is a significant hallmark of malignant tumors including GBM. Previous studies suggest that microRNAs play key roles in modulating this process in GBM cells.Expand
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MicroRNA-206 attenuates glioma cell proliferation, migration, and invasion by blocking the WNT/β-catenin pathway via direct targeting of Frizzled 7 mRNA.
Glioma is one of the most prevalent primary malignant brain tumours among adults, and accumulating evidence has shown that dysregulation of microRNAs (miRNAs) is associated with various types ofExpand
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MicroRNA-940 inhibits epithelial-mesenchymal transition of glioma cells via targeting ZEB2.
  • R. Xu, F. Zhou, +5 authors N. Liu
  • Biology, Medicine
  • American journal of translational research
  • 2019
MicroRNAs have been found ectopically expressed in many cancers and play essential roles in tumor EMT progress. Recent studies identified decreased miR-940 expression in glioma cells and may serve asExpand
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CRISPR-Cas13a system: a novel approach to precision oncology
TLDR
- Cite this article as: Zhang J, You Y. CRISPR-Cas13a system: a novel approach toprecision oncology. Expand
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