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Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease
The results imply that Aβ oligomers induce a potent inflammatory response and subsequently disturb microglial phagocytosis and clearance of Aβ fibrils, thereby contributing to an initial neurodegenerative characteristic of AD. Expand
Diversity of Rotavirus Strains among Children with Acute Diarrhea in China: 1998-2000 Surveillance Study
The results indicate that while the common rotavirus strains remain predominant, the diversity of strains is much greater than was previously recognized. Expand
Mechanism of alternative splicing and its regulation.
An in-depth understanding of alternative splicing regulation has the potential not only to elucidate fundamental biological principles, but to provide solutions for various diseases. Expand
Automatic detection and recognition of signs from natural scenes
This paper proposes a local intensity normalization method to effectively handle lighting variations, followed by a Gabor transform to obtain local features, and finally a linear discriminant analysis (LDA) method for feature selection. Expand
Periodontal Disease and Risk of Chronic Obstructive Pulmonary Disease: A Meta-Analysis of Observational Studies
Based on current evidence, PD is a significant and independent risk factor of COPD, however, whether a causal relationships exists remains unclear and performing randomized controlled trails to explore whether periodontal interventions are beneficial in regulating COPD pathogenesis and progression is suggested. Expand
Percutaneous sonographically guided microwave coagulation therapy for hepatocellular carcinoma: results in 234 patients.
Sonographically guided microwave coagulation proved to be safe and effective for the treatment of hepatocellular carcinoma and resulted in a high percentage of cases without evidence of residual tumor and satisfactory long-term results. Expand
Periodontal health, oral health behaviours, and chronic obstructive pulmonary disease.
Poor periodontal health, dental care, and oral health knowledge were significantly associated with an increased risk of COPD, indicating the importance of promoting dental care and Oral health knowledge that can be integrated into the prevention and treatment of COPd. Expand
Exercise training promotes expression of apelin and APJ of cardiovascular tissues in spontaneously hypertensive rats.
Long-term swimming training relieved the pathogenesis of hypertension and reversed the downregulation of the cardiovascular APelin/APJ system induced by hypertension, which suggests that the improving effect of exercise training on hypertension could be mediated by upregulating the cardiovascular apelin/ APJ system. Expand
Probiotics for Preventing Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of High-Quality Randomized Controlled Trials
Background Ventilator-associated pneumonia (VAP) is considered to be a worldwide issue along with the development of supportive ventilation. The preventing strategy is of great importance for itsExpand
Dynamics and spatial variability of near-bottom sediment exchange in the Yangtze Estuary, China
Abstract This study was conducted to examine the spatial variations in the exchange between near-bottom suspended and sea-bottom sediments in the Yangtze Estuary and adjacent region, as well as toExpand