• Publications
  • Influence
Progesterone Administration Modulates Cortical TLR4/NF-κB Signaling Pathway after Subarachnoid Hemorrhage in Male Rats
TLDR
It was concluded that post-SAH progesterone administration may attenuate TLR4/NF-κB signaling pathway in the rat brain following SAH, which significantly ameliorated the EBI. Expand
Diallyl trisulfide ameliorates myocardial ischemia–reperfusion injury by reducing oxidative stress and endoplasmic reticulum stress-mediated apoptosis in type 1 diabetic rats: role of SIRT1 activation
TLDR
Perioperative DATS treatment effectively ameliorates MI/R injury in type 1 diabetic setting by enhancing cardiac SIRT1 signaling, thus reducing myocardial apoptosis and eventually preserving cardiac function. Expand
Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth.
TLDR
The multiple roles of CCL2 in the tumor microenvironment make it an attractive therapeutic target in metastatic prostate cancer as well as in other cancers. Expand
A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease
TLDR
The results provide a previously undefined mechanism by which unregulated miR-30b causes synaptic and cognitive dysfunction in AD, suggesting that reversal of dysregulated miR -30b in the brain may prevent or slow cognitive declines in AD. Expand
Recombinant human erythropoietin (rhEPO) alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Nrf2-ARE pathway.
TLDR
Post-SAH rhEPO administration may attenuate EBI in this SAH model, possibly through activating Nrf2-ARE pathway and modulating cerebral oxidative stress by inducing antioxidant and detoxifying enzymes. Expand
Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia
TLDR
Bicyclol protected the rat brain from ischemic damage caused by MCAO, and this effect may be through the upregulation of the transcription factor Nrf2 expression. Expand
Melatonin alleviates aluminium chloride-induced immunotoxicity by inhibiting oxidative stress and apoptosis associated with the activation of Nrf2 signaling pathway.
TLDR
It is suggested that melatonin treatment may alleviate AlCl3-induced immunotoxicity by inhibiting oxidative stress and apoptosis associated with the activation of Nrf2 signaling pathway, which could lay the foundation for the treatment of AlCl 3 immunot toxicity. Expand
Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat
TLDR
It is concluded that NOB protected the brain from ischemic damage and it maybe through activating the Akt/CREB signaling pathway and ameliorating BBB permeability. Expand
Tumor necrosis factor receptor‐associated factor 6 participates in early brain injury after subarachnoid hemorrhage in rats through inhibiting autophagy and promoting oxidative stress
TLDR
Results indicated that TRAF6 affected the degree of EBI after SAH by inhibiting autophagy and promoting oxidative stress, including neuronal death, brain edema, and blood–brain barrier injury. Expand
...
1
2
3
4
5
...