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- Publications
- Influence
Further Characterization of the epa Gene Cluster and Epa Polysaccharides of Enterococcus faecalis
- F. Teng, K. Singh, Agathe Bourgogne, J. Zeng, B. Murray
- Biology, Medicine
- Infection and Immunity
- 6 July 2009
ABSTRACT We previously identified a gene cluster, epa (for enterocococcal polysaccharide antigen), involved in polysaccharide biosynthesis of Enterococcus faecalis and showed that disruption of epaB… Expand
Targeting DDX3 with a small molecule inhibitor for lung cancer therapy
Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which is… Expand
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
- J. Gehrke, O. Cervantes, +5 authors J. K. Joung
- Chemistry, Medicine
- Nature Biotechnology
- 30 July 2018
Base editor technology, which uses CRISPR–Cas9 to direct cytidine deaminase enzymatic activity to specific genomic loci, enables the highly efficient introduction of precise cytidine-to-thymidine DNA… Expand
Choroidal thickness in healthy Chinese subjects.
- X. Ding, Jia-qing Li, +5 authors Shi-bo Tang
- Medicine
- Investigative ophthalmology & visual science
- 2011
PURPOSE
To study posterior choroidal thickness and its profile based on location in a healthy Chinese population and to determine its correlation with age and refractive error.
METHODS
A total of… Expand
Improved Succinate Production by Metabolic Engineering
- Ke-ke Cheng, Gen-Yu Wang, J. Zeng, Jian-an Zhang
- Biology, Medicine
- BioMed research international
- 18 April 2013
Succinate is a promising chemical which has wide applications and can be produced by biological route. The history of the biosuccinate production shows that the joint effort of different metabolic… Expand
A profile of HIV risk factors in the context of sex work environments among migrant female sex workers in Beijing, China
Migrant female sex workers (FSWs) are one of the most at-risk populations for HIV in China. This study demonstrates how multiple risk factors are situated and vary by types of sex work environments… Expand
Ultrafine medicated fibers electrospun from W/O emulsions.
- X. Xu, Lixin Yang, +5 authors X. Jing
- Chemistry, Medicine
- Journal of controlled release : official journal…
- 2 November 2005
Ultrafine fibers containing water-soluble drugs were successfully electrospun from water-in-oil (W/O) emulsions, in which the aqueous phase contained the water-soluble drugs and the oily phase was a… Expand
Highly efficient therapeutic gene editing of human hematopoietic stem cells
Re-expression of the paralogous γ-globin genes (HBG1/2) could be a universal strategy to ameliorate the severe β-globin disorders sickle cell disease (SCD) and β-thalassemia by induction of fetal… Expand
The impact of hard and soft quality management on quality and innovation performance: An empirical study ☆
TLDR
Hematoporphyrin monomethyl ether photodynamic damage on HeLa cells by means of reactive oxygen species production and cytosolic free calcium concentration elevation.
- Xinmin Ding, Qinzhi Xu, +6 authors X. Li
- Chemistry, Medicine
- Cancer letters
- 8 December 2004
Hematoporphyrin monomethyl ether (HMME) is a novel and promising porphyrin-related photosensitizer for photodynamic therapy (PDT). HMME-PDT-induced cell death and its mechanisms were investigated in… Expand