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Further Characterization of the epa Gene Cluster and Epa Polysaccharides of Enterococcus faecalis
ABSTRACT We previously identified a gene cluster, epa (for enterocococcal polysaccharide antigen), involved in polysaccharide biosynthesis of Enterococcus faecalis and showed that disruption of epaBExpand
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Targeting DDX3 with a small molecule inhibitor for lung cancer therapy
Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which isExpand
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An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
Base editor technology, which uses CRISPR–Cas9 to direct cytidine deaminase enzymatic activity to specific genomic loci, enables the highly efficient introduction of precise cytidine-to-thymidine DNAExpand
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Choroidal thickness in healthy Chinese subjects.
PURPOSE To study posterior choroidal thickness and its profile based on location in a healthy Chinese population and to determine its correlation with age and refractive error. METHODS A total ofExpand
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Improved Succinate Production by Metabolic Engineering
Succinate is a promising chemical which has wide applications and can be produced by biological route. The history of the biosuccinate production shows that the joint effort of different metabolicExpand
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A profile of HIV risk factors in the context of sex work environments among migrant female sex workers in Beijing, China
Migrant female sex workers (FSWs) are one of the most at-risk populations for HIV in China. This study demonstrates how multiple risk factors are situated and vary by types of sex work environmentsExpand
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Ultrafine medicated fibers electrospun from W/O emulsions.
  • X. Xu, Lixin Yang, +5 authors X. Jing
  • Chemistry, Medicine
  • Journal of controlled release : official journal…
  • 2 November 2005
Ultrafine fibers containing water-soluble drugs were successfully electrospun from water-in-oil (W/O) emulsions, in which the aqueous phase contained the water-soluble drugs and the oily phase was aExpand
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Highly efficient therapeutic gene editing of human hematopoietic stem cells
Re-expression of the paralogous γ-globin genes (HBG1/2) could be a universal strategy to ameliorate the severe β-globin disorders sickle cell disease (SCD) and β-thalassemia by induction of fetalExpand
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The impact of hard and soft quality management on quality and innovation performance: An empirical study ☆
This study examines the conflicting relationship between quality management (QM) and innovation on a global basis using a multidimensional view of QM. Expand
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Hematoporphyrin monomethyl ether photodynamic damage on HeLa cells by means of reactive oxygen species production and cytosolic free calcium concentration elevation.
Hematoporphyrin monomethyl ether (HMME) is a novel and promising porphyrin-related photosensitizer for photodynamic therapy (PDT). HMME-PDT-induced cell death and its mechanisms were investigated inExpand
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