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The skeletal metastatic complications of renal cell carcinoma.
Of the 103 patients with advanced renal cell carcinoma 31 (30%) developed symptomatic radiologically confirmed skeletal metastases. These were typically lytic, predominantly affecting the axialExpand
Cetuximab-based therapy for metastatic colorectal cancer: a meta-analysis of the effect of K-ras mutations
BackgroundCetuximab has a favorable effect on patients with metastatic colorectal cancer harboring wild K-ras gene. This meta-analysis was planned to quantify the benefit.MethodsA meta-analysis ofExpand
Basal vs. luminal a breast cancer subtypes: a matched case-control study using estrogen receptor, progesterone receptor, and HER-2 as surrogate markers
Breast cancer is a heterogeneous disease that encompasses several distinct entities with different biological characteristics and clinical behavior. Basal subtype is considered as a prognosticallyExpand
Patterns of epidermal growth factor receptor mutation in non-small-cell lung cancers in the Gulf region.
The aim of the present study was to determine the prevalence of epidermal growth factor receptor mutations (EGFRmut) in the Gulf region (GR) and its correlation with demographic and clinicalExpand
Breaking Cancer Bad News to Patients With Cancer: A Comprehensive Perspective of Patients, Their Relatives, and the Public—Example From a Middle Eastern Country
Purpose Empowering patients with cancer requires that they be continuously informed about their condition. In some Eastern cultures, this concept is often opposed by caregivers. We aim to compare theExpand
The anti-tumour effects of zoledronic acid
Bone is the most common site for metastasis in patients with solid tumours. Bisphosphonates are an effective treatment for preventing skeletal related events and preserving quality of life in theseExpand
Platinum‐based adjuvant chemotherapy for early‐stage epithelial ovarian cancer: single or combination chemotherapy?
Please cite this paper as: Adams G, Zekri J, Wong H, Walking J, Green J. Platinum‐based adjuvant chemotherapy for early‐stage epithelial ovarian cancer: single or combination chemotherapy? BJOGExpand
Metastatic struma ovarii: late presentation, unusual features and multiple radioactive iodine treatments.
Metastatic malignant struma ovarii is rare and there is a lack of agreement on the criteria of diagnosis and the lines of management. Here we describe a patient with struma ovarii that was initiallyExpand
Folic acid supplementation for the prevention of recurrence of colorectal adenomas: metaanalysis of interventional trials
Conflicting data have emerged from preclinical and clinical studies that examined the relationship between folic acid and the risk of recurrence of colorectal adenomas. To determine precisely thatExpand
Chemotherapy for small cell lung cancer: a comprehensive review
Combination chemotherapy is the current strategy of choice for treatment of small cell lung cancer (SCLC). Platinum containing combination regimens are superior to non-platinum regimens in limitedExpand