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Diterpenoids from Croton laui and their cytotoxic and antimicrobial activities.
TLDR
Fourteen new diterpenoids including clerodane, labdane, and norlabdane types, as well as nine known analogues were isolated from the aerial parts of Croton laui, and crotonolide A exhibited moderate cytotoxicity against two tumor cell lines and significant antibacterial activity against a panel of Gram-positive bacteria.
Onoceranoid-type triterpenoids from Lansium domesticum.
A rare class of onoceranoid-type triterpenoids, represented by lamesticumin A (1), the ethanolysis product of lamesticumin A (2), lamesticumins B-F (3-7), lansic acid 3-ethyl ester (8), and ethyl
Trigochinins A-C: three new daphnane-type diterpenes from Trigonostemon chinensis.
TLDR
This study suggested the revision of the C-6 stereochemistry of trigonothyrins A-C reported quite recently, which showed significant inhibition against MET tyrosine kinase activity.
Alkaloids from Gelsemium elegans.
TLDR
Compounds 1-4 were evaluated for cytotoxic activity against four tumor cell lines, and gelsebamine selectively inhibited the A-549 human lung adenocarcinoma cell line.
Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity
TLDR
Astragaloside II enhances T cell activation by regulating the activity of CD45 PTPase, which may explain why Astragalus membranaceus Bge is used as a tonic herb in treating immunosuppressive diseases.
Two new lignan glycosides from Saussurea laniceps
Two new lignan glycosides, lanicepsides A and B (1 and 2), along with the eight known compounds 3–6, epipinoresinol, syringin, ethyl caffeate, and 5,6,7-trihydroxy-4′-methoxyflavone, including
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