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Concurrent choice for social interaction and amphetamine using conditioned place preference in rats: effects of age and housing condition.
BACKGROUND Social interaction can serve as a natural reward that attenuates drug reward in rats; however, it is unknown if age or housing conditions alter the choice between social interaction andExpand
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Social facilitation of d-amphetamine self-administration in rats.
The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of socialExpand
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Role of ionotropic glutamate receptors in delay and probability discounting in the rat
RationaleDiscounting of delayed and probabilistic reinforcement is linked to increased drug use and pathological gambling. Understanding the neurobiology of discounting is important for designingExpand
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High impulsivity in rats predicts amphetamine conditioned place preference
Stimulants such as d-amphetamine (AMPH) are used commonly to treat attention-deficit hyperactivity disorder (ADHD), but concerns have been raised regarding the use of AMPH due to its reinforcing andExpand
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Role of medial prefrontal and orbitofrontal monoamine transporters and receptors in performance in an adjusting delay discounting procedure
Performance in an adjusting delay discounting procedure is predictive of drug abuse vulnerability; however, the shared underlying specific prefrontal neural systems linking delay discounting andExpand
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A translational behavioral model of mood-based impulsivity: Implications for substance abuse.
BACKGROUND Laboratory tasks that measure various facets of impulsivity derived from self-report questionnaires are important for elucidating the behavioral consequences of impulsivity in humans andExpand
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Dissociable roles of dopamine and serotonin transporter function in a rat model of negative urgency
Negative urgency is a facet of impulsivity that reflects mood-based rash action and is associated with various maladaptive behaviors in humans. However, the underlying neural mechanisms of negativeExpand
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Effects of NMDA receptor antagonists on probability discounting depend on the order of probability presentation
Risky decision making can be measured using a probability-discounting procedure, in which animals choose between a small, certain reinforcer and a large, uncertain reinforcer. Recent evidence hasExpand
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Effects of Intra-Accumbal Administration of Dopamine and Ionotropic Glutamate Receptor Drugs on Delay Discounting Performance in Rats
Nucleus accumbens core (NAcc) has been implicated in impulsive choice, as measured in delay discounting. The role of dopamine (DA) in impulsive choice has received considerable attention, whereasExpand
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Environmental enrichment and drug value: a behavioral economic analysis in male rats
Rats raised in an enriched condition (EC) show decreased stimulant self‐administration relative to rats reared in an isolated condition (IC). However, few studies have examined the behavioralExpand
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