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A panel of five circulating microRNAs as potential biomarkers for prostate cancer
Circulating microRNA (miRNAs) have been shown to have the potential as noninvasive diagnosis markers in several types of cancers. In this study, we investigated whether circulating miRNAs could be… Expand
Baicalein Inhibits the Invasion and Metastatic Capabilities of Hepatocellular Carcinoma Cells via Down-Regulation of the ERK Pathway
Baicalein, a widely used Chinese herbal medicine, has historically been used in anti-inflammatory and anti-cancer therapies. However, the anti-metastatic effect and molecular mechanism(s) of… Expand
Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer
BackgroundUncontrolled proliferation and increased motility are hallmarks of neoplastic cells, therefore markers of proliferation and motility may be valuable in assessing tumor progression and… Expand
Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit
The ubiquitously expressed 14-3-3 proteins regulate many pathways involved in transformation. Previously, we found that 14-3-3ζ overexpression increased Akt phosphorylation in human mammary… Expand
Use of mobile phones in an emergency reporting system for infectious disease surveillance after the Sichuan earthquake in China.
- Changhong Yang, J. Yang, X. Luo, P. Gong
- Bulletin of the World Health Organization
- 1 August 2009
PROBLEM Quick detection and response were essential for preventing outbreaks of infectious diseases after the Sichuan earthquake. However, the existing public health communication system in Sichuan… Expand
Ceramide and other sphingolipids in cellular responses
Formerly considered to serve only as structural components, sphingolipids are emerging as an important group of signaling molecules involved in many cellular events, including cell growth,… Expand
Molecular identification and functional expression of porcine Toll-like receptor (TLR) 3 and TLR7.
- Y. Sang, J. Yang, C. Ross, R. R. Rowland, F. Blecha
- Biology, Medicine
- Veterinary immunology and immunopathology
- 15 September 2008
To investigate porcine Toll-like receptors (TLR) responding to viral pathogen associated molecular patterns, the full-length cDNA of porcine TLR3 and TLR7 were identified and characterized. Porcine… Expand
Decreased polysomal HSP-70 may slow polypeptide elongation during skeletal muscle atrophy.
- Z. Ku, J. Yang, V. B. Menon, D. Thomason
- Biology, Medicine
- The American journal of physiology
- 1 June 1995
Slowed elongation rate is the apparent cause of the rapid decrease in rat soleus muscle protein synthesis rate during non-weight bearing. We found that elongation factor 2 was not phosphorylated and… Expand
Molecular Phenotypes Distinguish Patients with Relatively Stable from Progressive Idiopathic Pulmonary Fibrosis (IPF)
Background Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic interstitial lung disease that is unresponsive to current therapy and often leads to death. However, the rate of disease… Expand
Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies.
Despite an increase in survival for children with acute lymphoblastic leukemia (ALL), the outcome after relapse is poor. To understand the genetic events that contribute to relapse and… Expand