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The orphan receptor GPR55 is a novel cannabinoid receptor.

• Emil Ryberg, Nils-Göran Larsson, +7 authors Peter J Greasley
• British journal of pharmacology
• 2007

BACKGROUND The endocannabinoid system functions through two well characterized receptor systems, the CB1 and CB2 receptors. Work by a number of groups in recent years has provided evidence that the… (More)

Astroglia and glutamate in physiology and pathology: aspects on glutamate transport, glutamate-induced cell swelling and gap-junction communication.

• Elisabeth Hansson, Håkan Muyderman, +6 authors Lars Rönnbäck
• Neurochemistry international
• 2000

Astroglia have the capacity to monitor extracellular glutamate (Glu) and maintain it at low levels, metabolize Glu, or release it back into the extracellular space. Glu can induce an increase in… (More)

Co-inheritance of Hb D-Punjab (codon 121; GAA-->CAA) and beta (0) -thalassemia (IVS-II-1;G-->A).

• Adekunle D. Adekile, E G Kazanetz, J. Y. Leonova, Rajaa A Marouf, A Khmis, T. H. Huisman
• Journal of pediatric hematology/oncology
• 1996

PURPOSE Homozygosity for Hb D-Punjab (or Hb D-Los Angeles; codon 121; GAA-->CAA) is rare among Arabs. The co-inheritance of Hb D with beta(0)-thalassemia trait is even rarer, with only 10 previous… (More)

Endothelin-1 decreases glutamate uptake in primary cultured rat astrocytes.

• J. Y. Leonova, Torleif Thorlin, N. David Åberg, Peter Eriksson, Lars Rönnbäck, Eva Hansson
• American journal of physiology. Cell physiology
• 2001

Endothelin-1 (ET-1) is a potent vasoconstrictor peptide that is also known to induce a wide spectrum of biological responses in nonvascular tissue. In this study, we found that ET-1 (100 nM)… (More)

Hb Hakkari or alpha 2 beta 2 31(B13)Leu-->Arg, a severely unstable hemoglobin variant associated with numerous intra-erythroblastic inclusions and erythroid hyperplasia of the bone marrow.

• Aytemiz Gürgey, Canan Altay, +4 authors T. H. Huisman
• Hemoglobin
• 1995

A severely unstable hemoglobin variant, Hb Hakkari or alpha 2 beta 2 31 (B13)Leu-->Arg, has been observed in a 5-year-old Turkish girl with a severe hemolytic anemia without Heinz body formation. A… (More)

A study of 45,X/46,XX mosaicism in Turner syndrome females: a novel primer pair for the (CAG)n repeat within the androgen receptor gene.

• J. Y. Leonova, Cynthia K. Hanson
• Hereditas
• 1999

This paper describes the procedures developed for the determining of diparental/uniparental origin of X chromosomes in mosaic Turner females (karyotype 45,X/46,XX), and accounts for results of the… (More)

Hb Costa Rica or alpha 2 beta 2 77(EF1)His --> Arg: the first example of a somatic cell mutation in a globin gene.

• W E Rodríguez Romero, M. M. Artigao Castillo, +7 authors T. H. Huisman
• Human genetics
• 1996

We have identified a minor hemoglobin component (approximately 5%) in the blood of a healthy Costa Rican female, but not in her mother and two brothers (father not studied), that has an His --> Arg… (More)

A de novo deletion causing epsilon gamma delta beta-thalassemia in a Dutch patient.

• Jules C. Abels, J. J. Michiels, +6 authors T. H. Huisman
• Acta haematologica
• 1996

The alpha / beta and alpha 2 / alpha 1-globin mRNA ratios in different forms of alpha-thalassemia.

• Natalija Smetanina, J. Y. Leonova, Nicolas Lévy, T. H. Huisman
• Biochimica et biophysica acta
• 1996

The present study provides information about the alpha / beta and alpha 2 / alpha 1-mRNA ratios in reticulocytes of normal adults and individuals with different alpha-globin gene deficiencies; it… (More)

Identification of several alpha-globin gene variations in a small Laotian family.

• Natalija Smetanina, J. Y. Leonova, Nicolas Lévy, T. H. Huisman
• Acta haematologica
• 1995

The present study concerns the identification of four alpha-globin gene deficiencies, one alpha 1-globin gene mutation, and one beta-globin gene mutation in a Laotian couple and their newborn baby.… (More)

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