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The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages.
This study examines the use of electrospun biodegradable polymers as scaffolds not only for enhancing the differentiation of mouse ES cells into neural lineages but also for promoting and guiding the neurite outgrowth.
Understanding the role of surface charges in cellular adsorption versus internalization by selectively removing gold nanoparticles on the cell surface with a I2/KI etchant.
An etching solution based on I2 and KI that can selectively dissolve the Au nanospheres on the cell surface within a short period of time is introduced that is capable of etching away a relatively large amount of Au Nanospheres at a low molar concentration.
Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells.
In vitro cellular uptake experimental results indicated that HepG2 cells prefer smaller nanoparticles with the same PEG configuration on their surfaces, and the cytotoxicity of paclitaxel-loaded nanoparticles seemed to increase with increasing drug loading of nanoparticles against HepG 2 cells.
Encapsulation of protein drugs in biodegradable microparticles by co-axial electrospray.
A co-axial electrospray process was developed to encapsulate protein-based drugs in biodegradable polymeric microparticles eliminating the key problem faced by other conventional methods of protein
Gold nanocages covered by smart polymers for controlled release with near-infrared light
This work develops a platform based on the photothermal effect of gold nanocages that works well with various effectors without involving sophiscated syntheses, and is well-suited for in vivo studies due to the high transparency of soft tissue in NIR.
Electrohydrodynamic atomization for biodegradable polymeric particle production.
EHDA is a promising technique to fabricate polymeric micro- or nanoparticles which can be used in drug delivery systems, and can be employed for controlled release applications.
Electrospray in the dripping mode for cell microencapsulation.
  • J. Xie, Chi‐Hwa Wang
  • Materials Science, Medicine
    Journal of colloid and interface science
  • 15 August 2007
The main objective of the present study was to investigate the droplet formation and to better develop mono-dispersed microencapsulation of living cells with controllable size.
Electrospun nanofibers for neural tissue engineering.
Insight is provided into methods for investigating the mechanisms of neurite growth on novel nanofibrous scaffolds and optimization of the nanofiber scaffolding and conduits for repairing peripheral nerve injuries.
Coating electrospun poly(epsilon-caprolactone) fibers with gelatin and calcium phosphate and their use as biomimetic scaffolds for bone tissue engineering.
Results indicated that the hybrid system containing poly(epsilon-caprolactone), gelatin, and calcium phosphate could serve as a new class of biomimetic scaffolds for bone tissue engineering.
Putting Electrospun Nanofibers to Work for Biomedical Research.
Electrospinning has been exploited for almost one century to process polymers and related materials into nanofibers with controllable compositions, diameters, porosities, and porous structures for a variety of applications that include controlled release, drug delivery, and tissue engineering.