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Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures.
Tanshinone is a group of active diterpenes widely used in treatment of cardiovascular diseases. Here, we report the introduction of genes encoding 3-hydroxy-3-methylglutaryl CoA reductase (HMGR),Expand
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Interaction of dietary polyphenols with bovine milk proteins: molecular structure-affinity relationship and influencing bioactivity aspects.
SCOPE Dietary flavonoids and stilbenes are important polyphenols in foods, such as, e.g. fruits, vegetables, nuts, and tea as they are of great interest for their bioactivities, which are related toExpand
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The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility
As of late, polyphenols have increasingly interested the scientific community due to their proposed health benefits. Much of this attention has focused on their bioavailability. Polyphenol–gutExpand
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A Review of Dietary Polyphenol-Plasma Protein Interactions: Characterization, Influence on the Bioactivity, and Structure-Affinity Relationship
  • J. Xiao, G. Kai
  • Chemistry, Medicine
  • Critical reviews in food science and nutrition
  • 1 January 2012
The interactions between polyphenols, especially flavonoids and plasma proteins, have attracted great interest among researchers. Few papers, however, have focused on the structure-affinityExpand
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Advances in the biotechnological glycosylation of valuable flavonoids.
The natural flavonoids, especially their glycosides, are the most abundant polyphenols in foods and have diverse bioactivities. The biotransformation of flavonoid aglycones into their glycosides isExpand
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Increased accumulation of the cardio-cerebrovascular disease treatment drug tanshinone in Salvia miltiorrhiza hairy roots by the enzymes 3-hydroxy-3-methylglutaryl CoA reductase and
Tanshinone is widely used for treatment of cardio-cerebrovascular diseases with increasing demand. Herein, key enzyme genes SmHMGR (3-hydroxy-3-methylglutaryl CoA reductase) and SmDXRExpand
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Kaempferol and inflammation: From chemistry to medicine.
Inflammation is an important process of human healing response, wherein the tissues respond to injuries induced by many agents including pathogens. It is characterized by pain, redness and heat inExpand
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Influence of B-ring hydroxylation on interactions of flavonols with bovine serum albumin.
  • J. Xiao, M. Suzuki, +4 authors M. Xu
  • Chemistry, Medicine
  • Journal of agricultural and food chemistry
  • 12 March 2008
The B-ring substitution pattern of flavonols is a significant structural feature for their function as free radical scavengers and antioxidants. In this paper, four differently substituted B-ringExpand
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Dietary flavonoid aglycones and their glycosides: Which show better biological significance?
  • J. Xiao
  • Chemistry, Medicine
  • Critical reviews in food science and nutrition
  • 15 July 2015
ABSTRACT The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets and are of great general interest due to their diverse bioactivity. The natural flavonoidsExpand
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A Review on Structure–Activity Relationship of Dietary Polyphenols Inhibiting α-Amylase
The inhibitory effects of dietary polyphenols against α-amylase have attracted great interest among researchers. The aim of this review is to give an overview of the research reports on theExpand
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