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Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds.
The aortic valve exhibits complex three-dimensional (3D) anatomy and heterogeneity essential for the long-term efficient biomechanical function. These are, however, challenging to mimic in de novoExpand
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Hydrophobic IR780 encapsulated in biodegradable human serum albumin nanoparticles for photothermal and photodynamic therapy.
It has been reported that IR780 iodide, a near-infrared dye, can be applied for cancer imaging, photodynamic therapy (PDT) and photothermal therapy (PTT). However, the hydrophobicity and toxicity ofExpand
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Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy
Photodynamic therapy (PDT) kills cancer cells by converting tumour oxygen into reactive singlet oxygen (1O2) using a photosensitizer. However, pre-existing hypoxia in tumours and oxygen consumptionExpand
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Angiographic outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes).
OBJECTIVES The PLATO (Platelet Inhibition and Patient Outcomes) angiographic substudy sought to compare the efficacy of ticagrelor versus clopidogrel with respect to angiographic outcomes before andExpand
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Self-assembled IR780-loaded transferrin nanoparticles as an imaging, targeting and PDT/PTT agent for cancer therapy
Combination of photothermal and photodynamic therapy (PTT/PDT) offer unique advantages over PDT alone. However, to achieve synergetic PDT/PTT effect, one generally needs two lasers with differentExpand
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Self-assembled PEG-IR-780-C13 micelle as a targeting, safe and highly-effective photothermal agent for in vivo imaging and cancer therapy.
IR-780, a representative hydrophobic near-infrared (NIR) fluorescence dye, is capable of fluorescently imaging and photothermal therapy in vitro and in vivo. However, insolubility in allExpand
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Flexible chemiresistor sensors: thin film assemblies of nanoparticles on a polyethylene terephthalate substrate
The thin film assembly of metal nanoparticles on flexible chemiresistor (CR) arrays represents an intriguing way to address the versatility of chemical sensor design. In this work, thin filmExpand
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Long noncoding RNA TCF7 promotes invasiveness and self-renewal of human non-small cell lung cancer cells
Lung cancer is the most common solid tumor and the leading cause of cancer-related death worldwide. Non-small cell lung cancer (NSCLC) represents the major histological subtype and accounts for aboutExpand
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In situ floating hydrogel for intravesical delivery of adriamycin without blocking urinary tract.
Drug solution is commonly used in conventional intravesical instillation. However, most of them would be easily eliminated by voiding, which significantly limit their efficacy. Recent advances inExpand
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Application of near-infrared dyes for tumor imaging, photothermal, and photodynamic therapies.
Near-infrared (NIR) dyes, small organic molecules that function in the NIR region, have received increasing attention in recent years as diagnostic and therapeutic agents in the field of tumorExpand
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