• Publications
  • Influence
PKA: a portrait of protein kinase dynamics.
High-resolution structures of the catalytic subunit of cAMP-dependent protein kinase and a new recombinantly expressed PKA reporter are described that allows us to monitor PKA activity in living cells and the molecular features of these molecules are described. Expand
Inhibition of the association of RNA polymerase II with the preinitiation complex by a viral transcriptional repressor.
This report characterized the mechanisms by which the immediate early protein 2 (IE2 or IE86), a master transcriptional regulator of human cytomegalovirus, down-regulates its own expression and presents data that suggest that this type of repression might be widely used in the control of transcription by RNA polymerase II. Expand
The role of IL‐12 and TNF‐α in AIDP and AMAN
Acute inflammatory demyelinating polyradiculoneuropathy and acute motor axonal neuropathy have been described as two major subtypes of Guillain‐Barré syndrome; however, the possible difference of their immune‐inflammatory pathogenesis remains unclear. Expand
Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis.
Findings indicate that the new antirejection agent rapamycin inhibits hepatic fibrosis and thus may become a valuable addition to the immunosuppression armamentarium. Expand
Isolation and characterization of a novel type of neurotoxic peptide from the venom of the South African scorpion Parabuthus transvaalicus (Buthidae).
The discovery of birtoxin, a bioactive long chain neurotoxin peptide with only three disulfide bridges, offers new insight into understanding the role of conserved disulfides bridges with respect to scorpion toxin structure and function. Expand
Cooperative Effects of Exercise Training and Genistein Administration on Bone Mass in Ovariectomized Mice
The results indicate that the combined intervention of moderate exercise and the submaximal dose of genistein administration show a cooperative effect in preventing bone loss in OVX mice. Expand
Linkage study of two polymorphisms at the dopamine D3 receptor gene and attention-deficit hyperactivity disorder.
The findings using this particular sample do not support the role of the dopamine D3 gene in ADHD, and the transmission of the alleles at either polymorphism or any haplotype is examined. Expand
Diffusion of ISO 14001 environmental management systems in China: rethinking on stakeholders’ roles
Abstract Since the release of ISO 14001 in 1996, China has witnessed a surge in the number of ISO 14001 certification. As an international environmental standard, ISO 14001 has two basic functions:Expand
Consumption of medium- and long-chain triacylglycerols decreases body fat and blood triglyceride in Chinese hypertriglyceridemic subjects
  • C. Xue, Y. Liu, +11 authors J. Wu
  • Chemistry, Medicine
  • European Journal of Clinical Nutrition
  • 21 January 2009
Consumption of MLCT may reduce body weight, body fat and blood TG in hypertriglyceridemic subjects under an appropriate dietary regime. Expand
AVAGAST: A randomized, double-blind, placebo-controlled, phase III study of first-line capecitabine and cisplatin plus bevacizumab or placebo in patients with advanced gastric cancer (AGC).
While the primary endpoint was not met, there was a significant improvement in PFS and ORR and an acceptable safety profile for bev + chemo in patients with AGC, and AVAGAST is the first randomized study to compare the efficacy and safety of bev+ chemo vs placebo +Chemo. Expand