• Publications
  • Influence
The Knockout Mouse Project
TLDR
It is time to harness new technologies and efficiencies of production to mount a high-throughput international effort to produce and phenotype knockouts for all mouse genes, and place these resources into the public domain.
Current challenges in de novo plant genome sequencing and assembly
TLDR
The state of the art of assembly is assessed, the best practices for the community are reviewed, and the challenges of assembling plant genomes de novo remain challenging.
Tackling antibiotic resistance
TLDR
To explore how the problem of antibiotic resistance might best be addressed, a group of 30 scientists from academia and industry gathered at the Banbury Conference Centre in Cold Spring Harbor, New York, USA, from 16 to 18 May 2011.
Beyond the gene: cytoplasmic inheritance and the struggle for authority in genetics
TLDR
This book is comparable with the Course Units the Open University publishes in Britain, but without the illustrations: it is a dauntingly serious work, and the students must derive much profit from their course, but the summaries are written in the style of historical introductions in good scientific texts and are highly compressed.
Direct Diagnostic Tests for Lyme Disease
TLDR
Reliable direct-detection methods for active B. burgdorferi infection have been lacking in the past but are needed and appear achievable, and new approaches have effectively been applied to other emerging infections and show promise in direct detection of B. burglars.
Picture control: the electron microscope and the transformation of biology in America, 1940–1960
TLDR
The author says that he "actually disliked it", an opinion that raises several questions about the motivation of the man credited with the introduction of chlorpromazine.
Advances in Serodiagnostic Testing for Lyme Disease Are at Hand
TLDR
Next-generation serologic assays, prepared with recombinant proteins or synthetic peptides, and alternative testing protocols, can now overcome or circumvent many of these past drawbacks.
The negative impact of intentionally introduced Quercus rubra L. on a forest community
TLDR
The results show that Q. rubra significantly reduces native species richness and abundance, both in old-growth and in secondary (post-agricultural) forests, and significantly limits the environmental functions of the POF ecosystem and weakens its economic and social aspects.
Redefining Genomic Privacy: Trust and Empowerment
TLDR
This work proposes shifting the paradigm of protecting human subjects to techniques that facilitate trust between researchers and participants and creates a zero-sum game of privacy versus data utility.
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