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Articles : Quantitative Analysis of Compounds in Fermented Insampaedok-san and Their Neuroprotective Activity in HT22 Cells
Insampaedok-san is a traditional medicine used for the treatment of colds. We investigated several compounds in Insampeadok-san, and tested their neuroprotective and anti-oxidative activities afterExpand
Cognitive Enhancing and Neuroprotective Effect of the Embryo of the Nelumbo nucifera Seed
It is found that ENS significantly ameliorated scopolamine-induced memory impairment and inhibited AChE activity in hippocampus and showed potent neuroprotective effects against glutamate-induced neurotoxicity in the HT22 cell. Expand
Neuroprotective Properties of Compounds Extracted from Dianthus superbus L. against Glutamate-induced Cell Death in HT22 Cells
D. superbus extract significantly protected on glutamate-induced cell death in HT22 cells and compounds isolated from it exhibited neuroprotective properties, suggesting therapeutic potential for applications in neurotoxic diseases. Expand
A HPLC-DAD method for the simultaneous determination of five marker components in the traditional herbal medicine Bangpungtongsung-san
This developed method was applied to the commercial Bangpungtongsungsung-san sample and the five marker components were separated effectively without interference of any peaks of components. Expand
Qualitative and quantitative simultaneous determination of six marker compounds in soshiho-tang by HPLC-DAD-ESI-MS
The HPLC-DAD-ESI-MS method was developed and validated for simultaneous determination of six marker compounds, namely homogentisic acid, baicalin, glycyrrhizin, saikosaponin A, 6-gingerol and ginsenoside Rg3 in Soshiho-tang and showed good linear regression. Expand
Neuroprotective compounds of Tilia amurensis
Five compounds isolated from T. amurensis had significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells, demonstrating that compound two, three, four, and five have a pronounced protective effect against neurotransmitter-induced neurotoxicity. Expand
Simultaneous quantification of marker components in Ojeok-san by HPLC–DAD
The results of validation showed that the HPLC method was stable and very accurate for the quantification of eight marker components in Ojeok-san, a traditional Korean herbal medicine. Expand
Cognitive-Enhancing Effect of Aronia melanocarpa Extract against Memory Impairment Induced by Scopolamine in Mice
Results showed that A. melanocarpa berries extract improved memory impairment by inhibiting AChE and increasing BDNF and p-CREB expression, and cyanidin-3-O-galactoside may be responsible for the effect. Expand
Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata
Results indicate that steamed and fermented C. lanceolata (SFC) extract protected HT22 cells by anti-oxidative effect and inhibition of the expression of Bax and caspase-3. Expand
Simultaneous determination of ten bioactive compaounds from the roots of Cynanchum paniculatum by using high performance liquid chromatography coupled-diode array detector
The results of validation appeared that this established method was very accurate and stabilized for the quantification of 10 bioactive compounds isolated from C. paniculatum. Expand