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Detection of hepatitis E virus (HEV) from porcine livers in Southeastern Germany and high sequence homology to human HEV isolates.
TLDR
The suggested role of undercooked pig products in food as a source of zoonotic HEV infection for humans remains to be clarified if this mechanism of transmission is responsible for the surprisingly high anti-HEV IgG prevalence recently observed in some European countries and the USA. Expand
Hepatitis E Virus Seroprevalence among Adults, Germany
TLDR
Overall HEV IgG prevalence was 16.8% (95% CI 15.6%–17.9%) and increased with age, leveling off at >60 years of age, and the lifetime risk for exposure is high. Expand
Prevalence of hepatitis E virus-specific antibodies in humans with occupational exposure to pigs
TLDR
An increased risk of HEV infection in humans occupationally exposed to pigs and particularly for slaughterers was demonstrated and one may assume a higher prevalence ofHEV-specific antibodies in humans with occupational exposure to pigs. Expand
Test performance characteristics of Anti-HEV IgG assays strongly influence hepatitis E seroprevalence estimates.
TLDR
3 frequently used tests for HEV detection are compared: the MP Diagnostics HEV immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA), the Axiom Diagnostics Hev IgG enzyme immunoassay (EIA), and the Mikrogen recomLine HEV IgG assay. Expand
Hepatitis A outbreak disproportionately affecting men who have sex with men (MSM) in the European Union and European Economic Area, June 2016 to May 2017
TLDR
Results depict an HA outbreak of multiple HAV strains, within a cross-European population, that was particularly driven by transmission between non-immune MSM engaging in high-risk sexual behaviour. Expand
Detection of influenza A(H1N1)v virus by real-time RT-PCR.
TLDR
A novel real-time RT-PCR assay for influenza A(H1N1)v virus was set up ad hoc and validated following industry-standard criteria and proved its principle and might assist public health laboratories in the upcoming influenza pandemic. Expand
Ongoing outbreaks of hepatitis A among men who have sex with men (MSM), Berlin, November 2016 to January 2017 – linked to other German cities and European countries
TLDR
Phylogenetic analysis revealed three distinct sequences, linking cases in Berlin to those in other German cities and to clusters recognised in other European countries in 2016. Expand
ABC A-subfamily transporters: structure, function and disease.
TLDR
Current knowledge on the role of ABC A-subfamily transporters in physiology and disease is summarized and clinical entities which may be potentially associated with dysfunctional members of this gene subfamily are explored. Expand
Molecular structure of a novel cholesterol-responsive A subclass ABC transporter, ABCA9.
We recently identified a novel ABC A subclass transporter, ABCA6, in human macrophages. Here, we report the molecular cloning of an additional ABC A subfamily transporter from macrophages denotedExpand
Adenosine triphosphate binding cassette (ABC) transporters are expressed and regulated during terminal keratinocyte differentiation: a potential role for ABCA7 in epidermal lipid reorganization.
TLDR
Findings support the notion that ABCB1 and ABCG1 are potentially implicated in cholesterol transport, whereas ABCC1, ABCC3, and ABCC4 are candidate regulators of the translocation of sulfated lipids during stratum corneum keratinization. Expand
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