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Theory of electroporation: A review
Abstract Electroporation is a membrane phenomenon which involves fundamental behavior of cell and artificial bilayer membranes, and increasingly attracts consideration for applications in biology,Expand
Electroporation: A general phenomenon for manipulating cells and tissues
  • J. Weaver
  • Biology, Medicine
  • Journal of cellular biochemistry
  • 1 April 1993
Electroporation is a fascinating cell membrane phenomenon with several existing biological applications and others likely. Although DNA introduction is the most common use, electroporation ofExpand
Microdosimetry for conventional and supra-electroporation in cells with organelles.
Conventional electroporation (EP) by 0.1 to 1 kV/cm pulses longer than 100 micros, and supra-electroporation by 10 to 300 kV/cm pulses shorter than 1 micros cause different cellular effects.Expand
Electroporation of cells and tissues
Electrical pulses that cause the transmembrane voltage of fluid lipid bilayer membranes to reach at least U/sub m//spl ap/0.2 V, usually 0.5-1 V, are hypothesized to create primary membrane "pores"Expand
Electrical properties of skin at moderate voltages: contribution of appendageal macropores.
The electrical properties of human skin in the range of the applied voltages between 0.2 and 60 V are modeled theoretically and measured experimentally. Two parallel electric current pathways areExpand
Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery.
Mammalian skin owes its remarkable barrier function to its outermost and dead layer, the stratum corneum. Transdermal transport through this region occurs predominantly through intercellular lipids,Expand
Theory of electroporation of planar bilayer membranes: predictions of the aqueous area, change in capacitance, and pore-pore separation.
A large increase in the transmembrane voltage, U(t), of a fluid bilayer membrane is believed to result in the occurrence of temporary aqueous pathways ("pores") across the membrane. The number, size,Expand
Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion
The heat transport system model of the skin was solved by exploiting the mathematical analogy between local thermal models and local electrical (charge transport) models, thereby allowing robust circuit simulation software to obtain solutions to Kirchhoff's laws for the system model. Expand
Changes in the passive electrical properties of human stratum corneum due to electroporation.
The stratum corneum (SC) is the main barrier to molecular and ionic transport across mammalian skin and has been extensively studied by others at low voltages (U(skin)(t) < 10 V) in order toExpand
Electroporation: a unified, quantitative theory of reversible electrical breakdown and mechanical rupture in artificial planar bilayer membranes☆
Abstract We present a quantitative theory of electroporation of artificial planar lipid bilayer membranes. Assuming that aqueous pores are involved in electroporation, we describe the pore populationExpand