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Wortmannin induces homotypic fusion of plant prevacuolar compartments*
Wortmannin, a specific inhibitor of phosphatidyl-inositol 3-kinase, is a useful tool for studying protein trafficking and identifying organelles in the plant secretory and endocytic pathways. It hasExpand
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Isolation and proteomic analysis of the SYP61 compartment reveal its role in exocytic trafficking in Arabidopsis
The endomembrane system is a complex and dynamic intracellular trafficking network. It is very challenging to track individual vesicles and their cargos in real time; however, affinity purificationExpand
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ARA7(Q69L) expression in transgenic Arabidopsis cells induces the formation of enlarged multivesicular bodies
Arabidopsis thaliana ARA7 (AtRabF2b), a member of the plant Rab5 small GTPases functioning in the vacuolar transport pathway, localizes to pre-vacuolar compartments (PVCs), known as multivesicularExpand
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Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance
  • X. Ma, Z. Chen, +24 authors X. Yao
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 14 April 2014
Significance A critical challenge for chemotherapy is development of chemoresistance, but underlying molecular mechanisms remain unclear. In this study, we found that drug-resistantExpand
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QUASIMODO 3 (QUA3) is a putative homogalacturonan methyltransferase regulating cell wall biosynthesis in Arabidopsis suspension-cultured cells
Pectins are complex polysaccharides that are essential components of the plant cell wall. In this study, a novel putative Arabidopsis S-adenosyl-L-methionine (SAM)-dependent methyltransferase, termedExpand
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Different Endomembrane Trafficking Pathways Establish Apical and Basal Polarities
The inhibitor endosin 16 defines a distinct pathway for endomembrane sorting via regulation of the small GTPase RabA that is essential for the establishment of cell polarity. The endomembrane systemExpand
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Protein Mobilization in Germinating Mung Bean Seeds Involves Vacuolar Sorting Receptors and Multivesicular Bodies1[W][OA]
Plants accumulate and store proteins in protein storage vacuoles (PSVs) during seed development and maturation. Upon seed germination, these storage proteins are mobilized to provide nutrients forExpand
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Unconventional protein secretion.
It is generally believed that protein secretion or exocytosis is achieved via a conventional ER (endoplasmic reticulum)-Golgi-TGN (trans-Golgi network)-PM (plasma membrane) pathway in the plantExpand
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SATB1 is overexpressed in metastatic prostate cancer and promotes prostate cancer cell growth and invasion
BackgroundSpecial AT-rich sequence binding protein 1 (SATB1) is a nuclear factor that functions as the global chromatin organizer to regulate chromatin structure and gene expression gene expression.Expand
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The rice RMR1 associates with a distinct prevacuolar compartment for the protein storage vacuole pathway.
Transport of vacuolar proteins from Golgi apparatus or trans-Golgi network (TGN) to vacuoles is a receptor-mediated process via an intermediate membrane-bound prevacuolar compartment (PVC) in plantExpand
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