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TGF-β Signaling Activates Steroid Hormone Receptor Expression during Neuronal Remodeling in the Drosophila Brain
It is concluded that the Drosophila Activin signaling pathway mediates neuronal remodeling in part by regulating EcR-B1 expression, which reduces expression of the ecdysone receptor B1 isoform (EcR- B1) and significantly rescues remodeling defects. Expand
Global genome expression analysis of rice in response to drought and high-salinity stresses in shoot, flag leaf, and panicle
Analysis of genome-level responses to drought and high-salinity stress in rice suggested that rice might possess a mechanism that actively detects rehydration and facilitates rapid recovery, supporting a notion that organ-specific gene regulation in response to the two abiotic stresses may primarily be mediated by organ- specific transcription responses. Expand
Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1α-dependent
  • L. Liu, Y. Lu, +9 authors Ruoning Wang
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 25 January 2016
It is reported that the mitogenic stimulus, colony-stimulating factor 1 (CSF-1), engages a myelocytomatosis viral oncogen (Myc)-dependent transcriptional program that is responsible for cell cycle entry and the up-regulation of glucose and glutamine catabolism in bone marrow-derived macrophages (BMDMs). Expand
Severe acute respiratory syndrome diagnostics using a coronavirus protein microarray.
It is shown that protein microarrays can serve as a rapid, sensitive, and simple tool for large-scale identification of viral-specific antibodies in sera and demonstrated that viral infection can be monitored for many months after infection. Expand
The tae-miR408-Mediated Control of TaTOC1 Genes Transcription Is Required for the Regulation of Heading Time in Wheat1[OPEN]
The results suggested that the tae-miR408 functions in the wheat heading time by mediating TaTOC1s expression, and the study provides important new information on the mechanism underlying heading time regulation in wheat. Expand
Dissecting yield-associated loci in super hybrid rice by resequencing recombinant inbred lines and improving parental genome sequences
The large recombinant inbred line population combined with plentiful high-quality single nucleotide polymorphisms and insertions/deletions between parental genomes allowed us to fine-map two quantitative trait loci, qSN8 and qSPB1, and to identify days to heading8 and lax panicle1 as candidate genes, respectively. Expand
Role for CysJ Flavin Reductase in Molybdenum Cofactor-Dependent Resistance of Escherichia coli to 6-N-Hydroxylaminopurine
The cysJ gene product is identified as one additional component of a novel Escherichia coli detoxification system for the removal of toxic and mutagenic N-hydroxylated nucleobases and related compounds that requires the molybdenum cofactor. Expand
Ankyrin G overexpression in Hutchinson-Gilford progeria syndrome fibroblasts identified through biological filtering of expression profiles
Differences in morphology, growth kinetics and mRNA expression profiles in HGPS cells compared to normal fibroblasts in culture are demonstrated, including increased expression of ANK3/ankyrin G. Expand
Genome-wide analysis of coding and non-coding RNA reveals a conserved miR164-NAC regulatory pathway for fruit ripening.
Multiple omics-based approaches revealed a novel regulatory link for fruit ripening that involved ethylene-miR164-NAC, a regulatory pathway present in various fruit (e.g. Rosaceae fruit, citrus, grape), with implications for Fruit ripening regulation. Expand