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The NCEP Climate Forecast System Reanalysis
The NCEP Climate Forecast System Reanalysis (CFSR) was completed for the 31-yr period from 1979 to 2009, in January 2010. The CFSR was designed and executed as a global, high-resolution coupledExpand
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Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
No Genetic Vertigo Peoples living in high altitudes have adapted to their situation (see the Perspective by Storz). To identify gene regions that might have contributed to high-altitude adaptation inExpand
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A Draft Sequence of the Rice Genome (Oryza sativa L. ssp. japonica)
The genome of the japonica subspecies of rice, an important cereal and model monocot, was sequenced and assembled by whole-genome shotgun sequencing. The assembled sequence covers 93% of theExpand
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Comparative genomics reveals insights into avian genome evolution and adaptation
Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian speciesExpand
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A User's Guide to the Encyclopedia of DNA Elements (ENCODE)
The mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the scientific and medical communities to interpret the human genome sequence and apply it to understand human biologyExpand
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A Draft Sequence for the Genome of the Domesticated Silkworm (Bombyx mori)
We report a draft sequence for the genome of the domesticated silkworm (Bombyx mori), covering 90.9% of all known silkworm genes. Our estimated gene count is 18,510, which exceeds the 13,379 genesExpand
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Distinct DNA methylomes of newborns and centenarians
  • H. Heyn, N. Li, +20 authors M. Esteller
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 11 June 2012
Human aging cannot be fully understood in terms of the constrained genetic setting. Epigenetic drift is an alternative means of explaining age-associated alterations. To address this issue, weExpand
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An integrated encyclopedia of DNA elements in the human genome
The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project hasExpand
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Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
“Normal” for the gut microbiota For the benefit of future clinical studies, it is critical to establish what constitutes a “normal” gut microbiome, if it exists at all. Through fecal samples andExpand
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An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia
Whole-genome data indicate that early modern humans expanded into Australia 62,000 to 75,000 years ago. We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hairExpand
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