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Compound heterozygosity for two non‐synonymous polymorphisms in NPC1L1 in a non‐responder to ezetimibe
Ezetimibe reduces plasma low‐density lipoprotein (LDL) cholesterol by blocking sterol absorption in enterocytes. The NPC1L1 gene product was recently identified as the molecular target for ezetimibe,Expand
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Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration
Plasma total homocysteine (tHcy) concentration, an independent risk factor of atherosclerosis, has numerous genetic and environmental determinants. While the thermolabile polymorphism in MTHFRExpand
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Production and anti-diabetic activity of soluble dietary fiber from apricot pulp by Trichoderma viride fermentation.
Soluble dietary fiber (SDF) was prepared by Trichoderma viride fermentation by using apricot pulp as the raw material. A four-factor and three-level response surface methodology was applied toExpand
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Kinetic modeling as a tool to understand the influence of cell culture process parameters on the glycation of monoclonal antibody biotherapeutics
Glycation, the nonenzymatic reaction between the reducing sugar glucose and the primary amine residues on amino acid side chains, commonly occurs in the cell culture supernatant during production ofExpand
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21 SF3B1 MUTATIONS INDUCE ABERRANT SPLICING LEADING TO A BLOCK IN ERYTHROID DIFFERENTIATION AND COMPETITIVE ADVANTAGE
20 SOMATIC MUTATIONAL MODEL TO PREDICT RESPONSE TO HYPOMETHYLATING AGENTS IN MYELODYSPLASTIC SYNDROMES A. Nazha1, T. Radivoyevitch2, S. Thota2, H. Makishima2, B. Patel2, D. Seastone1, H. Carraway1,Expand
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Amplification of the Full-Length PAMP Gene and Difference of the mRNA Expression Among Three Lean Pig Breeds
Abstract To understand the function of porcine adipocyte-special membrane protein (PAMP) gene and the difference of fat deposition ability among various lean pig breeds, a full-length porcineExpand
Composes macrocycliques utiles en tant qu'agents parmaceutiques
La presente invention concerne des compositions contenant des composes ayant la formule (I) et elle concerne egalement leurs methodes d'utilisation dans le traitement de divers troubles notamment desExpand
63–69........ REDUCTION OF CaMKII EXPRESSION IN THE HIPPOCAMPUS OF RATS FROM INGESTION OF FLUORIDE AND/OR LEAD
SKELETAL FLUORIDE IN KANGAROOS NEAR AN ALUMINIUM SMELTER 112............ BONE FLUORIDE CONCENTRATIONS OF EASTERN GREY KANGAROOS (MACROPUS GIGANTEUS) RESIDENT NEAR AN ALUMINIUM SMELTER INExpand
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Procédés de pronostic de l'aptitude à traiter le cancer d'un composé analogue de la zéaralénone
La presente invention porte sur des procedes de pronostic de l'aptitude d'un compose analogue de la zearalenone a traiter un cancer dans un sujet, sur des procedes de pronostic de l'aptitude d'unExpand
Composés alcéniques tétrasubstitués et leur utilisation
L'invention concerne des composes, ou des sels pharmaceutiquement acceptables de ceux-ci, et des procedes d'utilisation de ces composes pour le traitement du cancer du sein par l'administration d'uneExpand
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