• Publications
  • Influence
Population pharmacokinetics of intravenous polymyxin B in critically ill patients: implications for selection of dosage regimens.
BACKGROUND Polymyxin B is a last-line therapy for multidrug-resistant gram-negative bacteria. There is a dearth of pharmacokinetic data to guide dosing in critically ill patients. METHODSExpand
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The Prognostic Superiority of Log Odds of Positive Lymph Nodes in Stage III Colon Cancer
BackgroundLiterature showed that lymph node ratio (LNR) and total number of lymph nodes (TNODS) are independent prognostic factors in node-positive colon cancer. Our study assesses the prognosticExpand
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Coding deficits in hidden hearing loss induced by noise: the nature and impacts
Hidden hearing refers to the functional deficits in hearing without deterioration in hearing sensitivity. This concept is proposed based upon recent finding of massive noise-induced damage on ribbonExpand
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Comparison of three optical coherence tomography scanning areas for detection of glaucomatous damage.
PURPOSE Several cross-sectional studies have demonstrated the capability of optical coherence tomography (OCT) to detect glaucomatous changes. OCT enables posterior pole scanning of three regions:Expand
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Comparison of a Lymph Node Ratio–Based Staging System With the 7th AJCC System for Gastric Cancer: Analysis of 18,043 Patients From the SEER Database
Objectives:The American Joint Committee on Cancer (AJCC) staging system for gastric cancer bases N status on absolute number of metastatic nodes, regardless of the number of examined nodes. WeExpand
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A plasma microRNA panel for early detection of colorectal cancer
Colonoscopy remains the standard screening method for detecting colorectal cancer (CRC) at an early stage. However, many people avoid having a colonoscopy because of the fear for its potentialExpand
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Renal Disposition of Colistin in the Isolated Perfused Rat Kidney
  • Z. Ma, J. Wang, +4 authors R. Milne
  • Medicine, Biology
  • Antimicrobial Agents and Chemotherapy
  • 20 April 2009
ABSTRACT Nephrotoxicity is an important limitation to the clinical use of colistin against Pseudomonas aeruginosa and other gram-negative pathogens. Previous work reported net tubular reabsorption ofExpand
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Intratumoral IL-17+ Cells and Neutrophils show Strong Prognostic Significance in Intrahepatic Cholangiocarcinoma
BackgroundInflammatory reactions at a tumor site have both detrimental and beneficial effects on tumor progression. This study was designed to assess the clinical significance of tumor-infiltratingExpand
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Paroxetine to Treat Irritable Bowel Syndrome Not Responding to High-Fiber Diet: A Double-Blind, Placebo-Controlled Trial
OBJECTIVE:The purpose of the trial was to determine whether a high-fiber diet (HFD) alone or in combination with paroxetine or placebo was effective treatment for patients with irritable bowelExpand
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Wide Excision or Mohs Micrographic Surgery for the Treatment of Primary Dermatofibrosarcoma Protuberans
Objectives:Dermatofibrosarcoma protuberans (DFSP) is a spindle cell tumor with a high local recurrence rate. Wide excision (WE) has been the standard treatment, but ideal margin width is poorlyExpand
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