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Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I.
Membrane-type matrix metalloproteinase I (MT1-MMP)-deficient mice were found to have severe defects in skeletal development and angiogenesis. The craniofacial, axial, and appendicular skeletons wereExpand
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The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions
Watermelon, Citrullus lanatus, is an important cucurbit crop grown throughout the world. Here we report a high-quality draft genome sequence of the east Asia watermelon cultivar 97103 (2n = 2× = 22)Expand
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Target analysis by integration of transcriptome and ChIP-seq data with BETA
The combination of ChIP-seq and transcriptome analysis is a compelling approach to unravel the regulation of gene expression. Several recently published methods combine transcription factor (TF)Expand
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Luminous Infrared Galaxies in the Local Universe
We study the morphology and star formation properties of 159 local luminous infrared galaxies (LIRGs) using multicolor images from Data Release 2 (DR2) of the Sloan Digital Sky Survey (SDSS). TheExpand
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Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging.
Apoptosis-inducing factor (AIF) and AIF-homologous mitochondrion-associated inducer of death (AMID) are both mitochondrial flavoproteins that trigger caspase-independent apoptosis. PhylogeneticExpand
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The draft genomes of soft–shell turtle and green sea turtle yield insights into the development and evolution of the turtle–specific body plan
The unique anatomical features of turtles have raised unanswered questions about the origin of their unique body plan. We generated and analyzed draft genomes of the soft-shell turtle (PelodiscusExpand
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Ypt1 recruits the Atg1 kinase to the preautophagosomal structure
When macroautophagy, a catabolic process that rids the cells of unwanted proteins, is initiated, 30–60 nm Atg9 vesicles move from the Golgi to the preautophagosomal structure (PAS) to initiateExpand
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Activation of SOCS-3 by Resistin
ABSTRACT Resistin is an adipocyte hormone that modulates glucose homeostasis. Here we show that in 3T3-L1 adipocytes, resistin attenuates multiple effects of insulin, including insulin receptor (IR)Expand
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“Pseudo” γ-Butyrolactone Receptors Respond to Antibiotic Signals to Coordinate Antibiotic Biosynthesis*
  • G. Xu, J. Wang, +5 authors H. Tan
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 18 June 2010
In actinomycetes, the onset of secondary metabolite biosynthesis is often triggered by the quorum-sensing signal γ-butyrolactones (GBLs) via specific binding to their cognate receptors. However, theExpand
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Na(+)-dependent purine nucleoside transporter from human kidney: cloning and functional characterization.
Many purine nucleosides and their analogs are actively transported in the kidney. Using homology cloning strategies and reverse transcriptase-polymerase chain reactions, we isolated a cDNA encoding aExpand
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