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The 3–7 fragment of angiotensin II is probably responsible for its psychoactive properties
The abilities of angiotensin II-(3-7)-pentapeptide (A-II-(3-7), 1 nmol) and angiotensin II (A-II, 1 nmol) to influence rat's psychomotor and cognitive behaviours were compared. Both peptides, givenExpand
  • 77
Behavioral effects of angiotensin II and angiotensin II-(4-8)-pentapeptide in rats
One nM of angiotensin II (AII) or angiotensin II-(4-8)-pentapeptide [AII(4-8)] given intracerebroventricularly did not affect locomotor and exploratory behavior of rats in open field. AIIExpand
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Psychotropic activity of angiotensin II and its fragments Val-Tyr-Ile-NH2 and Val-Tyr-Ile-His-NH2.
Angiotensin II (A II) significantly enhanced the motor activity of rats in the open field as measured by forward locomotion, rearings and bar approaches while the tripeptide [A II(3-5)] and theExpand
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