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Certain malignant B cells rely on B-cell receptor (BCR)-mediated survival signals. Spleen tyrosine kinase (Syk) initiates and amplifies the BCR signal. In in vivo analyses of B-cell lymphoma cell… (More)
Although patients with relapsed Hodgkin's disease have a poor prognosis with conventional therapies, high-dose chemotherapy and autologous hematopoietic stem cell transplantation… (More)
8058 Background: Recent reports suggest that medical imaging, besides potentially harmful, could turn out neither cost- effective, nor beneficial. We investigated whether this can be justified in the… (More)
The value of anti-infectious prophylaxis for patients receiving R-CHOP is unclear. While the rate of grade 3&4 infections in elderly patients under (R)-CHOP is around 20%, we observed a higher rate… (More)