• Publications
  • Influence
Psychometric properties of the Penn Alcohol Craving Scale.
BACKGROUND This study introduces the Penn Alcohol Craving Scale (PACS), which has been used in several clinical trials at the University of Pennsylvania's Treatment Research Center. The PACS is aExpand
  • 477
  • 45
Reliability and validity of the Cocaine Selective Severity Assessment.
This article assesses the reliability and validity of the Cocaine Selective Severity Assessment (CSSA), a measure of cocaine abstinence signs and symptoms. Interrater reliability and scale internalExpand
  • 196
  • 23
A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients.
This study examined the association between two specific polymorphisms of the gene encoding the mu-opioid receptor and treatment outcomes in alcohol-dependent patients who were prescribed naltrexoneExpand
  • 284
  • 18
A Functional Polymorphism of the μ-Opioid Receptor Gene is Associated with Naltrexone Response in Alcohol-Dependent Patients
This study examined the association between two specific polymorphisms of the gene encoding the μ-opioid receptor and treatment outcomes in alcohol-dependent patients who were prescribed naltrexoneExpand
  • 506
  • 12
Concurrent naltrexone and prolonged exposure therapy for patients with comorbid alcohol dependence and PTSD: a randomized clinical trial.
IMPORTANCE Alcohol dependence comorbid with posttraumatic stress disorder (PTSD) has been found to be resistant to treatment. In addition, there is a concern that prolonged exposure therapy for PTSDExpand
  • 168
  • 11
  • PDF
Naltrexone in the treatment of alcohol dependence.
Seventy male alcohol-dependent patients participated in a 12-week, double-blind, placebo-controlled trial of naltrexone hydrochloride (50 mg/d) as an adjunct to treatment following alcoholExpand
  • 1,016
  • 10
Effect of naltrexone on alcohol "high" in alcoholics.
OBJECTIVE Subjective effects of alcohol in alcoholics treated with naltrexone or placebo were compared. METHOD In a previously reported double-blind clinical trial of 50 mg/day of naltrexone orExpand
  • 314
  • 9
A comparison of the effects of the opioid antagonists naltrexone, naltrindole, and beta-funaltrexamine on ethanol consumption in the rat.
The effects of the universal opioid antagonist naltrexone were compared to the delta-selective opioid antagonist naltrindole and the mu-selective opioid antagonist beta-funaltrexamine on ethanolExpand
  • 145
  • 9
Predicting treatment response to naltrexone: the influence of craving and family history.
Naltrexone has repeatedly been shown to reduce drinking in alcohol-dependent patients. Previous clinical research suggests that naltrexone may be more effective at reducing drinking among patientsExpand
  • 198
  • 9
Alcohol craving predicts drinking during treatment: an analysis of three assessment instruments.
OBJECTIVE The purpose of this investigation was to examine the utility of thee craving instruments to predict drinking during treatment. The three assessments used were the Penn Alcohol Craving ScaleExpand
  • 130
  • 9