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CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease
We performed a case–control study of Parkinson's disease (PD) in a population characterized by a high prevalence of pesticide exposure and studied the joint effect of pesticide exposure and CYP2D6.Expand
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Immunosuppressive therapy is more effective than interferon in neuromyelitis optica
To determine long-term treatment (LTT) of neuromyelitis optica (NMO), we retrospectively reviewed therapies of 26 patients with NMO followed in five French neurological departments. To assess LTTExpand
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Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study.
Excess of nitric oxide (NO) has been shown to exert neurotoxic impacts in the brain. Moreover, inhibition of two NO-synthesizing enzymes, neuronal NOS (nNOS) and inducible NOS (iNOS), displaysExpand
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Midlife Blood Pressure, Plasma &bgr;-Amyloid, and the Risk for Alzheimer Disease: The Honolulu Asia Aging Study
&bgr;-Amyloid (A&bgr;), a vasoactive protein, and elevated blood pressure (BP) levels are associated with Alzheimer disease (AD) and possibly vascular dementia. We investigated the joint associationExpand
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DAD-6: A 6-ltem Version of the Disability Assessment for Dementia Scale Which May Differentiate Alzheimer’s Disease and Mild Cognitive Impairment from Controls
Background: The need to detect early changes in instrumental activities of daily life led us to modify the Disability Assessment for Dementia Scale (DAD) by focusing on executive components of 6Expand
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Robot services for elderly with cognitive impairment: testing usability of graphical user interfaces.
BACKGROUND Socially assistive robotics for elderly care is a growing field. However, although robotics has the potential to support elderly in daily tasks by offering specific services, theExpand
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Coronary Artery Calcium, Brain Function and Structure: The AGES-Reykjavik Study
Background and Purpose— Several cardiovascular risk factors are associated with cognitive disorders in older persons. Little is known about the association of the burden of coronary atherosclerosisExpand
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Plasma amyloid levels within the Alzheimer's process and correlations with central biomarkers
Diagnostic relevance of plasma amyloid β (Aβ) for Alzheimer's disease (AD) process yields conflicting results. The objective of the study was to assess plasma levels of Aβ42 and Aβ40 in amnestic mildExpand
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Risk factors of multiple system atrophy: A case‐control study in French patients
Multiple system atrophy (MSA) is a rare sporadic progressive neurodegenerative disorder. MSA risk factors are poorly known. The objectives of this case‐control study were to study environmental riskExpand
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Computerized cognitive stimulation and engagement programs in older adults with mild cognitive impairment: comparing feasibility, acceptability, and cognitive and psychosocial effects
Purpose Mild cognitive impairment (MCI) is associated with a higher risk of dementia and is becoming a topic of interest for pharmacological and nonpharmacological interventions. With advances inExpand
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