J. Vińa

Publications45
h-index15
Citations1,210
Highly Influential Citations27
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Exhaustive physical exercise causes oxidation of glutathione status in blood: prevention by antioxidant administration.
We have studied the effect of exhaustive concentric physical exercise on glutathione redox status and the possible relationship between blood glutathione oxidation and blood lactate and pyruvate… Expand
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Xanthine oxidase is involved in exercise-induced oxidative stress in chronic obstructive pulmonary disease.
In the present study, we hypothesized that exhaustive exercise in patients with chronic obstructive pulmonary disease (COPD) results in glutathione oxidation and lipid peroxidation and that xanthine… Expand
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A high-performance liquid chromatography method for measurement of oxidized glutathione in biological samples.
A high-performance liquid chromatography method to determine oxidized glutathione (GSSG) in biological samples with ultraviolet-visible detection using N-ethylmaleimide to prevent reduced glutathione… Expand
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Decreased urea synthesis in cafeteria-diet-induced obesity in the rat.
Feeding rats with a cafeteria diet resulted in increases in total body weight and in epididymal-adipose-tissue weight. Those rats excreted significantly less N than did controls. The amount of N… Expand
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Maintenance of glutathione content is isolated hepatocyctes.
1. During the standard procedure for the preparation of rat hepatocytes, about half of the cellular GSH (reduced glutathione) is lost. 2. This loss is prevented by the addition of 0.1 mM-EGTA (but no… Expand
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Determination of oxidized glutathione in blood: high-performance liquid chromatography.
Publisher Summary The measurement of glutathione status is important in determining oxidative stress in tissues and biological fluids. The ratio of reduced to oxidized glutathione (GSH/GSSG) is a… Expand
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The effect of cysteine and N-acetyl cysteine on rat liver glutathione (GSH).
L'injection IP de cysteine et de N-acetylcysteine (NAC) reduit la teneur en GSH du foie du rat. Cependant l'injection de cysteine provoque toujours des depletions plus elevees de GSH que l'injection… Expand
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Physiological changes in glutathione metabolism in foetal and newborn rat liver.
Glutathione metabolism was studied in isolated hepatocytes from foetal, newborn and adult rats. The GSH/GSSG ratio decreased 15-20-fold through the foetal-neonatal-adult transition. This was mainly… Expand
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Late onset administration of oral antioxidants prevents age-related loss of motor co-ordination and brain mitochondrial DNA damage.
We have studied the effect of aging on brain glutathione redox ratio, on brain mitochondrial DNA damage and on motor co-ordination in mice and the possible protective role of late onset… Expand
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The effect of cysteine oxidation on isolated hepatocytes.
Isolated hepatocytes incubated with 4mM-cysteine lose reduced glutathione, adenine nucleotides and intracellular enzymes, thus showing extensive membrane damage. The toxic effects of cysteine are… Expand
  • 79