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IL-4 induces functional cell-surface expression of CXCR4 on human T cells.
Here we report that IL-4 specifically enhances cell surface expression of CXCR4 on resting peripheral and cord blood T cells. Whereas polarized Th2 clones express variable levels of CXCR4, expressionExpand
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Full-length cytokeratin-19 is released by human tumor cells: a potential role in metastatic progression of breast cancer
IntroductionWe evaluated whether CK19, one of the main cytoskeleton proteins of epithelial cells, is released as full-length protein from viable tumor cells and whether this property is relevant forExpand
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Comparative evaluation of three assays for the quantitation of human immunodeficiency virus type 1 RNA in plasma
Reverse transcriptase‐coupled polymerase chain reaction (Amplicor HIV‐1 Monitor), the branched DNA (bDNA) method (Quantiplex HIV‐1 RNA) and the nucleic acid sequence‐based assay (NASBA HIV‐1 RNA QT)Expand
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Cell-free Tumor DNA in Blood Plasma As a Marker for Circulating Tumor Cells in Prostate Cancer
Purpose: Circulating cell-free DNA in the blood of cancer patients harbors tumor-specific aberrations. Here, we investigated whether this DNA might also reflect the presence of circulating tumorExpand
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Detection and characterization of putative metastatic precursor cells in cancer patients.
Metastasis is the major cause of cancer-related death. Single disseminated tumor cells (DTC) can be detected in the bone marrow and peripheral blood years before the occurrence of clinicallyExpand
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Cytokines and Cell Surface Molecules Independently Induce CXCR4 Expression on CD4+ CCR7+ Human Memory T Cells1
In the present study, we show that IL-2, IL-4, IL-7, and IL-15 are able to induce functional CXCR4 surface expression on resting in vitro-generated CD4+ CXCR4− CCR7+ memory T cells. Cytokine-mediatedExpand
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Detection of memory B lymphocytes specific to hepatitis B virus (HBV) surface antigen (HBsAg) from HBsAg-vaccinated or HBV-immunized subjects by ELISPOT assay.
To improve the investigation of the role of human memory B lymphocytes following hepatitis B virus (HBV) infection or vaccination, we developed a method to characterize circulating memory B cellsExpand
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Impairment of B‐lymphocyte differentiation induced by dual triggering of the B‐cell antigen receptor and CD40 in advanced HIV‐1‐disease
Objective:This study was performed to investigate the hyporeactivity of purified B lymphocytes from HIV-1-infected patients. Design:Given the importance of the B-cell Ag receptor (BCR) and CD40 inExpand
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CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs
BackgroundTransmission of human immunodeficiency virus type 1 (HIV-1) through breast-feeding may involve both cell-free and cell-associated virus. This latter viral reservoir remains, however, to beExpand
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Circulating epithelial cells in patients with benign colon diseases.
BACKGROUND Detection of circulating tumor cells (CTCs) in the peripheral blood is a rapidly developing research field with clear clinical implications for the staging and monitoring of cancerExpand
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