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Downregulation of the CB1 Cannabinoid Receptor and Related Molecular Elements of the Endocannabinoid System in Epileptic Human Hippocampus
Endocannabinoid signaling is a key regulator of synaptic neurotransmission throughout the brain. Compelling evidence shows that its perturbation leads to development of epileptic seizures, thusExpand
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Loss of Calbindin-D28K immunoreactivity from dentate granule cells in human temporal lobe epilepsy
The loss of the calcium binding protein, Calbindin-D28k, from dentate granule cells has been observed in different animal models of epilepsy and in ischaemia. This decrease is accompanied byExpand
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Long-term outcome after temporal lobe surgery—Prediction of late worsening of seizure control
We analyzed possible predictors of late worsening of seizure control in 94 adult patients who had anterior temporal lobectomy (ATL) from the Epilepsy Center of the National Institute of PsychiatryExpand
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Surgery of ventral intradural midline cervical spinal pathologies via anterior cervical approach: our experience.
INTRODUCTION The surgical removal of the cervical intradural pathologies located ventrally carries a high risk. According to the anatomical situation and the increasing experience with anteriorExpand
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Loss and reorganization of calretinin-containing interneurons in the epileptic human hippocampus.
Calretinin is expressed mainly in interneurons that specialize to innervate either principal cell dendrites or other interneurons in the human hippocampus. Calretinin-containing cells were shown toExpand
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Histopathologic evaluation of aneurysms treated with Guglielmi detachable coils or matrix detachable microcoils.
BACKGROUND AND PURPOSE The purpose of this study was to evaluate the degree of organization and fibrocellular tissue development in aneurysms treated with bare platinum or biologically activeExpand
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Dynamic changes of CB1‐receptor expression in hippocampi of epileptic mice and humans
The endocannabinoid system plays a central role in retrograde synaptic communication, and controls both glutamatergic and γ‐aminobutyric acid (GABA)ergic transmission via type 1 cannabinoid (CB1)Expand
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Contralateral approach to bilateral and ophthalmic aneurysms.
In a previous survey, we found a high incidence of fatal rupture of an unclipped aneurysm in patients with multiple aneurysms. To deal with this problem, we introduced a more vigorous technique thatExpand
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Intrinsic innervation of the urinary bladder.
The intrinsic innervation of the urinary bladder of the cat was studied with the aid of total extrinsic denervation (L7, S1, S2, S3 and the first coccygeal spinal nerves were transected and theExpand
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Ultrastructure of the nerve cells and fibres in the urinary bladder wall of the cat.
The nerve elements in the urinary bladder of the cat were studied by electron microscopy. According to their ultrastructure, nerve cell somata can be classified into three types: the large cells withExpand
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