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Composition and analysis of cerebrospinal fluid in clinically normal adult cattle.
Cerebrospinal fluid and serum were obtained from 16 clinically normal adult cows (11 dairy, 5 beef). Sodium, potassium, magnesium, total protein, and albumin concentrations, osmolality, and lactateExpand
Pharmacokinetics of ciprofloxacin in ponies.
The pharmacokinetics of ciprofloxacin was investigated in healthy, mature ponies. Ciprofloxacin was administered intravenously to six ponies at a dose of 5 mg per kg body weight. Seven days later,Expand
The isolation and characterisation of (3R,5R)- and (3S,5R)-carbapenam-3-carboxylic acid from Serratia and Erwinia species and their putative biosynthetic role
Two new β-lactams (4b) and (5b), and (3S,5R)-carbapenam-3-carboxylic acid, have been isolated from strains of Serratia and Erwinia spp.; their possible role, and that ofExpand
Advances in the therapy for mastitis.
Methods to enhance mammary resistance to bacterial infection and to reduce the effects of existing infections without the use of antimicrobial agents are becoming more attractive, primarily becauseExpand
The identification of three new biosynthetic intermediates and one further biosynthetic enzyme in the clavulanic acid pathway
Labelling experiments are described that identify three new compounds, N2-(2-carboxyethyl)arginine, 5-guanidino-(2-oxoazetidin-1-yl)pentanoic acid, andExpand
Evidence that the immediate biosynthetic precursor of clavulanic acid is its N-aldehyde analogue
(3R, 5R) Clavulanate-9-aldehyde 1 has been detected in Streptomyces clavuligerus and an NADPH dependent dehydrogenase capable of reducing 1 to clavulanic acid 2 has been isolated from this organism.
SB-202742, a novel beta-lactamase inhibitor isolated from Spondias mombin.
SB-202742 [1], an anacardic acid derivative possessing beta-lactamase inhibitory activity, has been isolated from a hexane extract of the plant, Spondias mombin. Its isolation, structureExpand
Evaluation of assays for determination of passive transfer status in neonatal llamas and alpacas.
OBJECTIVE To evaluate several practice-adapted assays for determination of passive transfer status in crias. ANIMALS 24 llama and 9 alpaca crias. DESIGN Prospective study. PROCEDURE Serum IgGExpand
Intramammary administration of gentamicin as treatment for experimentally induced Escherichia coli mastitis in cows.
In 8 Holstein cows, 50 colony-forming units (CFU) of Escherichia coli was administered into 1 mammary gland. Infections were established in all inoculated glands. In 4 of the 8 cows, 500 mg ofExpand
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