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Advantages and disadvantages of using artificial neural networks versus logistic regression for predicting medical outcomes.
- J. Tu
- Computer Science, Medicine
- Journal of clinical epidemiology
- 1 November 1996
Artificial neural networks are algorithms that can be used to perform nonlinear statistical modeling and provide a new alternative to logistic regression, the most commonly used method for developing predictive models in medicine. Expand
Outcome of heart failure with preserved ejection fraction in a population-based study.
BACKGROUND The importance of heart failure with preserved ejection fraction is increasingly recognized. We conducted a study to evaluate the epidemiologic features and outcomes of patients with heart… Expand
A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
- D. Juurlink, T. Gomes, +6 authors M. Mamdani
- Canadian Medical Association Journal
- 31 March 2009
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical significance of this drug interaction is unknown. Methods: We conducted a… Expand
Impact of hospital nursing care on 30-day mortality for acute medical patients.
AIM This paper reports on structures and processes of hospital care influencing 30-day mortality for acute medical patients. BACKGROUND Wide variation in risk-adjusted 30-day hospital mortality… Expand
Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of women for bone densitometry.
- S. M. Cadarette, S. Jaglal, N. Kreiger, W. McIsaac, G. Darlington, J. Tu
- CMAJ : Canadian Medical Association journal…
- 2 May 2000
BACKGROUND Although mass screening for osteoporosis is not recommended among postmenopausal women, there is no consensus on which women should undergo testing for low bone mineral density. The… Expand
Deriving Ethnic-Specific BMI Cutoff Points for Assessing Diabetes Risk
OBJECTIVE The definition of obesity (BMI ≥30 kg/m2), a key risk factor of diabetes, is widely used in white populations; however, its appropriateness in nonwhite populations has been questioned. We… Expand
Effects of socioeconomic status on access to invasive cardiac procedures and on mortality after acute myocardial infarction.
BACKGROUND Universal health care systems seek to ensure access to care on the basis of need rather than income and to improve the health status of all citizens. We examined the performance of the… Expand
Safety and Efficacy of Drug-Eluting and Bare Metal Stents: Comprehensive Meta-Analysis of Randomized Trials and Observational Studies
Background— The safety and efficacy of drug-eluting stents (DES) among more generalized “real-world” patients than those enrolled in pivotal randomized controlled trials (RCTs) are controversial. We… Expand
Relation of Disease Pathogenesis and Risk Factors to Heart Failure With Preserved or Reduced Ejection Fraction: Insights From the Framingham Heart Study of the National Heart, Lung, and Blood…
Background— The contributions of risk factors and disease pathogenesis to heart failure with preserved ejection fraction (HFPEF) versus heart failure with reduced ejection fraction (HFREF) have not… Expand
Bootstrap Methods for Developing Predictive Models
Researchers frequently use automated model selection methods such as backwards elimination to identify variables that are independent predictors of an outcome under consideration. We propose using… Expand