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Molecular cytogenetic analysis of head and neck squamous cell carcinoma: By comparative genomic hybridization, spectral karyotyping, and expression array analysis
TLDR
A combination of molecular cytogenetic and expression array analysis has been performed on head and neck squamous cell carcinoma of the oral cavity and supraglottis to determine whether genes located in these genomic regions are subject to alterations in gene expression. Expand
Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas.
TLDR
The data suggest that the depletion of nonsterol mevalonate metabolites, particularly GGPP, can be potential mediators of lovastatin-induced apoptosis of HNSCC and CC cells. Expand
Prospective validation of quantitative fluorescent polymerase chain reaction for rapid detection of common aneuploidies
TLDR
Quantitative fluorescent PCR is a robust and accurate method of rapid prenatal aneuploidy detection and compared with the karyotype results and the results of interphase fluorescence in situ hybridization testing, when performed in the course of standard care. Expand
DMI-1, a new DNA methyltransferase inhibitor produced by Streptomyces sp. strain No. 560.
TLDR
DMI-1 is a novel inhibitor of methyltransferase isolated from microorganisms and is structurally different from sinefungin and A9145C which are structural analogs of S-adenosylmethionine (methyl donor). Expand
Inhibition of DNA methyltransferase by microbial inhibitors and fatty acids.
TLDR
The results suggest that the length of the carbon chain, the number of double bonds and the presence of a carboxyl group and branched methyl group in the fatty acid molecule may play an important role in the inhibition of DNA methyltransferase. Expand
DMI-2 and DMI-3, DNA methyltransferase inhibitors produced by Streptomyces sp. strain no. 560.
TLDR
DMI-2 and DMI-3 showed strong inhibition against N6-methyladenine-DNA methyltransferase (M. Eco RI) and Eco RI in a competitive manner with respect to plasmid pUC19 and SAM. Expand
Molecular Analysis of a New Variant of the CBFβ - MYH11 Gene Fusion
TLDR
It is postulate that these two fusions arose from a single rearranged chromosome 16 by way of alternative splicing and were associated with a good prognosis in this patient with AML M4Eo. Expand
Molecular analysis of a new variant of the CBF beta-MYH11 gene fusion.
TLDR
It is postulate that these two fusions arose from a single rearranged chromosome 16 by way of alternative splicing and were associated with a good prognosis in this patient with AML M4Eo. Expand