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- Publications
- Influence
Glucose clamp technique: a method for quantifying insulin secretion and resistance.
- R. DeFronzo, J. Tobin, R. Andres
- Medicine
- The American journal of physiology
- 1 September 1979
Methods for the quantification of beta-cell sensitivity to glucose (hyperglycemic clamp technique) and of tissue sensitivity to insulin (euglycemic insulin clamp technique) are described.… Expand
Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging.
- S. Harman, E. Metter, J. Tobin, J. Pearson, M. Blackman
- Biology, Medicine
- The Journal of clinical endocrinology and…
- 1 February 2001
Many studies have shown cross-sectional (and two small studies, longitudinal) declines in total and/or free testosterone (T) levels, with age, in men. The extent to which decline in T is the result… Expand
Muscle quality. I. Age-associated differences between arm and leg muscle groups.
To determine the differences between arm and leg muscle quality (MQ) across the adult life span in men and women, concentric (Con) and eccentric (Ecc) peak torque (PT) were measured in 703 subjects… Expand
Longitudinal Studies on the Rate of Decline in Renal Function with Age
- R. Lindeman, J. Tobin, N. Shock
- Medicine
- Journal of the American Geriatrics Society
- 1 April 1985
Serial creatinine clearances (5 to 14 studies) were obtained for 446 normal volunteers in the Baltimore Longitudinal Study of Aging followed between 1958 and 1981. When those subjects with possible… Expand
The role of muscle loss in the age-related decline of grip strength: cross-sectional and longitudinal perspectives.
- D. A. Kallman, C. Plato, J. Tobin
- Medicine
- Journal of gerontology
- 1 May 1990
The decline of strength with age has often been attributed to declining muscle mass in older subjects. To investigate factors which might influence changes in strength across the life span, grip… Expand
A model of the kinetics of insulin in man.
- R. Sherwin, K. J. Kramer, +4 authors R. Andres
- Medicine
- The Journal of clinical investigation
- 1 May 1974
The design of the present study of the kinetics of insulin in man combines experimental features which obviate two of the major problems in previous insulin studies. (a) The use of radioiodinated… Expand
Impact of age on weight goals.
- R. Andres, D. Elahi, J. Tobin, D. C. Muller, L. Brant
- Medicine
- Annals of internal medicine
- 1 December 1985
Although the health hazards due to excessive obesity and excessive leanness are multiple and diverse, weight recommendations for over 40 years have been based solely on the risk of dying. The weight… Expand
The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study.
Standard true 24-hour creatinine clearance determinations were performed on 884 subjects of the Baltimore Longitudinal Study. On the basis of clinical data, subjects were placed in categories… Expand
Oral glucose augmentation of insulin secretion. Interactions of gastric inhibitory polypeptide with ambient glucose and insulin levels.
- D. Andersen, D. Elahi, J. Brown, J. Tobin, R. Andres
- Chemistry, Medicine
- The Journal of clinical investigation
- 1 July 1978
Gastric inhibitory polypeptide, or GIP, has been postulated as the major enteric hormonal mediator of insulin release. The release of immuno-reactive GIP (IR-GIP) after oral glucose and its role in… Expand
Muscle quality and age: cross-sectional and longitudinal comparisons.
- E. Metter, N. Lynch, R. Conwit, R. Lindle, J. Tobin, B. Hurley
- Medicine
- The journals of gerontology. Series A, Biological…
- 1 May 1999
We addressed whether muscle quality (force per unit muscle mass) changes with age in cross-sectional and longitudinal analyses from three groups from the Baltimore Longitudinal Study of Aging: (1)… Expand