J. Tiihonen

Publications511
h-index71
Citations16,364
Highly Influential Citations639
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A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia.
OBJECTIVE Data on the effectiveness of antipsychotics in the early phase of schizophrenia are limited. The authors examined the risk of rehospitalization and drug discontinuation in a nationwide… Expand
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11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
BACKGROUND The introduction of second-generation antipsychotic drugs during the 1990s is widely believed to have adversely affected mortality of patients with schizophrenia. Our aim was to establish… Expand
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Specific major mental disorders and criminality: a 26-year prospective study of the 1966 northern Finland birth cohort.
OBJECTIVE The purpose of the study was to examine the quantitative risk of criminal behavior associated with specific mental disorders. METHOD An unselected 1966 birth cohort (N = 12,058) in… Expand
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Mental disorders and homicidal behavior in Finland.
BACKGROUND Owing to the fact that Finnish police have been able to solve about 95% of all homicides during recent decades and because most homicide offenders are subjected to an intensive psychiatric… Expand
  • 375
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Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up…
Abstract Objective To study the association between prescribed antipsychotic drugs and outcome in schizophrenia or schizoaffective disorder in the community. Design Prospective cohort study using… Expand
  • 336
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  • PDF
Quantitative MRI of the hippocampus and amygdala in severe depression.
BACKGROUND There is little evidence to support possible structural changes in the amygdala and hippocampus of patients with severe depression. METHODS Quantitative MRI of the amygdala and… Expand
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A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence.
OBJECTIVE Problems related to illegal amphetamine use have become a major public health issue in many developed countries. To date, evidence on the effectiveness of psychosocial treatments has… Expand
  • 161
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Premorbid intellectual functioning in bipolar disorder and schizophrenia: results from a cohort study of male conscripts.
OBJECTIVE Premorbid intellectual impairment has been described in schizophrenia, but little is known about premorbid intellectual functioning in bipolar disorder or other psychoses. In this study,… Expand
  • 164
  • 12
Schizophrenia, Alcohol Abuse, and Violent Behavior: A 26-Year Followup Study of an Unselected Birth Cohort
It has been suggested that schizophrenia and alcoholism are associated with violent behavior. But so far there are no published studies from unselected cohorts quantifying the actual risk associated… Expand
  • 198
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Cortex and amygdala morphology in psychopathy
Psychopathy is characterized by abnormal emotional processes, but only recent neuroimaging studies have investigated its cerebral correlates. The study aim was to map local differences of cortical… Expand
  • 116
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