Should clearance be normalised to body surface or to lean body mass?
- T. Hallynck, H. Soep, J. Thomis, J. Boelaert, R. Daneels, L. Dettli
- MedicineBritish Journal of Clinical Pharmacology
- 1 May 1981
Prediction of creatinine clearance from serum creatinine concentration based on lean body mass
- T. Hallynck, H. Soep, L. Dettli
- Biology, MedicineClinical pharmacology and therapy
- 1 September 1981
In patients with rapidly changing renal function the new equation resulted in accurate predictions of CrCl within a few hours after the change, as opposed to several days with the other methods.
Lean body mass and amikacin dosage.
- T. Hallynck, H. Soep, J. Fillastre
- MedicineJournal of Antimicrobial Chemotherapy
- 1 March 1980
SOTALOL AND THE Q-Tc INTERVAL
- E. Lockhart, J. Thomis
- MedicineThe Lancet
- 3 October 1981
Creatinine clearance, different methods of determination.
- J. Thomis, H. Soep, T. Hallynck, J. Boelaert, R. Daneels, L. Dettli
- MedicineBritish Journal of Clinical Pharmacology
- 1 February 1982
Preparation and properties of 5-phenylphenoxymethylpenicillin.
- H. Vanderhaeghe, J. Thomis
- Chemistry, BiologyJournal of Medicinal Chemistry
- 1 May 1975
Compound 5 was debenzylated to 5-phenylphenoxymethylpenicillin potassium salt and the antibacterial activity of 8 was low, whereas the 6-epimer 9 was inactive.
Synthesis of deuterium- and tritium-labeled 6 beta-bromopenicillanic acid.
- P. Claes, H. Vanderhaeghe, E. Roets, J. Thomis, F. de Meester, J. Piette
- ChemistryJournal of antibiotics (Tokyo. )
- 1985
The synthesis of 6 beta-bromopenicillanic acid labeled with deuterium and tritium in the beta-methyl group is described and the two epimers are separated by column chromatography.
PREPARATION AND PROPERTIES OF 5-PHENYLPHENOXYMETHYLPENICILLIN
- H. Vanderhaeghe, J. Thomis
- Chemistry
- 2 September 1975
[The effect of modifications of the "penam" part of penicillin o].
- H. Vanderhaeghe, E. Roets, J. Thomis, H. Eyssen
- Chemistry, MedicineVerhandelingen - Koninklijke Academie voor…
- 1976