Should clearance be normalised to body surface or to lean body mass?
Prediction of creatinine clearance from serum creatinine concentration based on lean body mass
In patients with rapidly changing renal function the new equation resulted in accurate predictions of CrCl within a few hours after the change, as opposed to several days with the other methods.
Lean body mass and amikacin dosage.
SOTALOL AND THE Q-Tc INTERVAL
Creatinine clearance, different methods of determination.
Preparation and properties of 5-phenylphenoxymethylpenicillin.
Compound 5 was debenzylated to 5-phenylphenoxymethylpenicillin potassium salt and the antibacterial activity of 8 was low, whereas the 6-epimer 9 was inactive.
Synthesis of deuterium- and tritium-labeled 6 beta-bromopenicillanic acid.
- P. Claes, H. Vanderhaeghe, E. Roets, J. Thomis, F. de Meester, J. Piette
- ChemistryJournal of antibiotics (Tokyo. )
The synthesis of 6 beta-bromopenicillanic acid labeled with deuterium and tritium in the beta-methyl group is described and the two epimers are separated by column chromatography.