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HPLC method for evaluation of the free radical-scavenging activity of foods by using 1,1-diphenyl-2-picrylhydrazyl.
- T. Yamaguchi, H. Takamura, T. Matoba, J. Terao
- Chemistry, Medicine
- Bioscience, biotechnology, and biochemistry
- 23 June 1998
An HPLC method using 1,1-diphenyl-2-picrylhydrazyl (DPPH) determined the free radical-scavenging activity of several antioxidants: ascorbic acid, alpha-tocopherol, Trolox, and cysteine, and the results well agree with those of previous reports. Expand
Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the…
Zerumbone is a food phytochemical that has distinct potentials for use in anti-inflammation, chemoprevention, and chemotherapy strategies, and alpha-humulene, a structural analog lacking only the carbonyl group in ZER, was virtually inactive in all experiments conducted, indicating that the alpha,beta-unsaturated carbony l group may play some pivotal roles in interactions with unidentified target molecule(s). Expand
Absorption of chlorogenic acid and caffeic acid in rats after oral administration.
- K. Azuma, K. Ippoushi, M. Nakayama, H. Ito, H. Higashio, J. Terao
- Medicine, Chemistry
- Journal of agricultural and food chemistry
- 7 October 2000
The results suggest that chlorogenic acid is not well absorbed from the digestive tract, unlike caffeic acid, and subject to almost no structural changes to the easily absorbed forms. Expand
Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans
RA contained in PE was absorbed, conjugated and methylated following intake, with a small proportion of RA being degraded into various components, such as conjugate forms of CAA, FA and COA and these metabolites were then rapidly excreted in the urine. Expand
Multitargeted cancer prevention by quercetin.
Dietary quercetin is a promising agent for cancer prevention and further research is warranted, as it prevents chemically induced carcinogenesis and modulates several signal transduction pathways involving MEK/ERK and Nrf2/keap1. Expand
Protective effect of epicatechin, epicatechin gallate, and quercetin on lipid peroxidation in phospholipid bilayers.
It is concluded that catechins and quercetin serve as powerful antioxidants against lipid peroxidation when phospholipid bilayers are exposed to aqueous oxygen radicals. Expand
Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers
EC in chocolate and cocoa was partly absorbed and was found to be present as a component of various conjugates in plasma, and these were rapidly excreted in urine. Expand
Antioxidant Activity of Caffeic Acid and Dihydrocaffeic Acid in Lard and Human Low-Density Lipoprotein†
Caffeic acid (CA) has been implied as an important source of natural antioxidants in various agricultural products. We compared the antioxidative activity of CA and dihydrocaffeic acid (HCA) in lard… Expand
Absorption and urinary excretion of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in rats.
- S. Baba, N. Osakabe, M. Natsume, J. Terao
- Chemistry, Medicine
- Free radical biology & medicine
- 1 July 2002
Procyanidin B2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions and also degraded to (-)-epicatechin and to the metabolized conjugated and/or methylated (-)-Epicatechin internally in the rat. Expand
Unique uptake and transport of isoflavone aglycones by human intestinal caco-2 cells: comparison of isoflavonoids and flavonoids.
Results strongly suggest that isoflavone aglycones are taken up into enterocytes more efficiently than their glucosides because of their moderate lipophilicity and generally transported to the basolateral side in intact form in contrast to flavonoids, probably due to their unique is oflavonoid structure. Expand