• Publications
  • Influence
An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene.
Previous studies on the regulation of a Ucp minigene in transgenic mice demonstrated that the sequences necessary for brown-fat-specific expression and inducibility by norepinephrine were located inExpand
  • 174
  • 10
Functional Role of C-Terminal Cytoplasmic Tail of Rat Vanilloid Receptor 1
The vanilloid receptor [transient receptor potential (TRP)V1, also known as VR1] is a member of the TRP channel family. These receptors share a significant sequence homology, a similar predictedExpand
  • 178
  • 9
Ethanol inhibits cold‐menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5‐bisphosphate
Ethanol has opposite effects on two members of the transient receptor potential (TRP) family of ion channels: it inhibits the cold‐menthol receptor TRPM8, whereas it potentiates the activity of theExpand
  • 58
  • 9
Reducing and Oxidizing Agents Sensitize Heat-Activated Vanilloid Receptor (TRPV1) Current
We have previously reported that the reducing agent dithiothreitol (DTT) strongly increases thermally induced activity of the transient receptor potential vanilloid receptor-1 (TRPV1) channel. Here,Expand
  • 96
  • 8
  • PDF
14-3-3 proteins: a family of versatile molecular regulators.
The 14-3-3 proteins are a family of acidic regulatory molecules found in all eukaryotes. 14-3-3 proteins function as molecular scaffolds by modulating the conformation of their binding partners.Expand
  • 122
  • 5
  • PDF
Calmodulin and S100A1 Protein Interact with N Terminus of TRPM3 Channel*
Background: Calcium-binding proteins bind to intracellular termini of TRP channels. Results: Two Ca2+-dependent binding sites for CaM/S100A1 were revealed by biophysical methods on TRPM3 N terminus.Expand
  • 35
  • 5
Identification of P2X4 receptor-specific residues contributing to the ivermectin effects on channel deactivation.
Ivermectin (IVM) applied extracellularly increases the sensitivity of P2X4 receptor (P2X4R) to ATP, enhances the maximum current amplitudes, and greatly prolongs the deactivation kinetics. In thisExpand
  • 54
  • 4
Conserved Residues within the Putative S4–S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels*
The vanilloid transient receptor potential channel TRPV1 is a tetrameric six-transmembrane segment (S1–S6) channel that can be synergistically activated by various proalgesic agents such asExpand
  • 54
  • 4
  • PDF
Absorption and elimination of inhaled benzene in man.
  • 40
  • 3
14-3-3ζ C-terminal Stretch Changes Its Conformation upon Ligand Binding and Phosphorylation at Thr232*
14-3-3 proteins are abundant binding proteins involved in many biologically important processes. 14-3-3 proteins bind to other proteins in a phosphorylation-dependent manner and function as scaffoldExpand
  • 67
  • 3