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Efficacy and safety of cyclosporin a ophthalmic emulsion in the treatment of moderate-to-severe dry eye disease: A dose-ranging, randomized trial☆
Abstract Objective : To investigate the efficacy, safety, formulation tolerability, and optimal dosing of a novel cyclosporin A oil-in-water emulsion formulation for the treatment of… Expand
Immunosuppressive drugs in immune and inflammatory ocular disease.
Advances in immunology, particularly ocular immunology, have been accompanied by the emergence of safer, more specific immunosuppressive drugs, notably, cyclophosphamide, chlorambucil, methotrexate,… Expand
Improved Detection of Disease Progression in Ocular Cicatricial Pemphigoid
Cicatricial pemphigoid is an autoimmune systemic disease characterized by chronic conjunctival cicatrization. The natural history is one of variable degrees of progressive scarring of the ocular… Expand
Glaucoma in patients with ocular cicatricial pemphigoid.
This retrospective review of 111 patients with ocular cicatricial pemphigoid (CP) identifies 29 patients (26%) with glaucoma. Twenty-seven of these patients had a history of glaucoma for a mean of… Expand
An analysis of therapeutic decision making regarding immunosuppressive chemotherapy for peripheral ulcerative keratitis.
We reviewed our experience in the management of 47 patients (61 eyes) with peripheral ulcerative keratitis (PUK) to establish guidelines for appropriate indications to consider institution of… Expand
Cataract surgery in ocular cicatricial pemphigoid.
The authors report the results of their experience with cataract surgery in 20 patients (26 eyes) with biopsy-proven cicatricial pemphigoid. All patients were on systemic immunosuppression at the… Expand
Molecular Cloning, Sequence Analysis, Expression, and Tissue Distribution of Suppressin, a Novel Suppressor of Cell Cycle Entry*
- R. D. Leboeuf, E. Bán, +4 authors J. Tauber
- Biology, Medicine
- The Journal of Biological Chemistry
- 2 January 1998
Suppressin (SPN) is an inhibitor of cell proliferation that was originally identified and purified to homogeneity from bovine pituitaries (LeBoeuf, R. D., Burns, J. N., Bost, K. L., and Blalock, J.… Expand
Romberg's progressive hemifacial atrophy: an association with scleral melting.
- T. Hoang-Xuan, C. S. Foster, F. Jakobiec, J. Tauber, M. Sainz de la Maza, W. Krebs
- 1 July 1991
We report the unusual case of a 43-year-old woman who presented with Romberg's progressive facial hemiatrophy and spontaneous scleral perforation in the ipsilateral eye, for which scleral grafting… Expand
Pseudo-Kayser-Fleischer ring of the cornea associated with non-Wilsonian liver disease. A case report and literature review.
The Kayser-Fleischer ring of the cornea is usually considered a pathognomonic finding of Wilson's disease. A case of a Kayser-Fleischer ring associated with non-Wilsonian liver disease is presented.… Expand
Plasmapheresis treatment in patients with severe atopic keratoconjunctivitis.
A 19-year-old woman with hyperimmunoglobulinemia E (the hyper-IgE syndrome [HIE]) and a 62-year-old man with atopic dermatitis experienced dramatic improvement in their chronic ocular symptoms and… Expand