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Bone Induction by BMPs/OPs and Related Family Members in Primates: The Critical Role of Delivery Systems
This work focuses on the geometric induction of bone formation by sintered porous hydroxyapatite (SPHA) discs with concavities on their planar surfaces, which elicit bone formation without exogenously applied BMPs/OPs. Expand
Induction of Endochondral Bone Formation by Recombinant Human Transforming Growth Factor-β2 in the Baboon (Papio ursinus)
In the primate, TGF-βs themselves are inducers of endochondral bone formation, although the present data strongly indicate that the bone inductive activity of hTGF- β2 is site and tissue specific. Expand
Advances in biotechnology for tissue engineering of bone.
Although the BMP family of proteins and osteogenesis have been the subject of several recent reviews, this work focuses here on their activity in primates and on the novel localization of BMPs in the cerebellum and other areas of the nervous system, and the "mosaicism" of their localisation in the periodontal tissues. Expand
The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry
It is suggested that the surface chemistry of these materials may not be the most critical factor in the development of growth of a functional monolayer of RPE cells as long as the cells can attach and proliferate on the surface. Expand