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Soft Actor-Critic Algorithms and Applications
We introduce Soft Actor-Critic, an off-policy actor-critic algorithm based on the maximum entropy RL framework that achieves state-of-the-art performance in sample-efficiency and asymptotic performance. Expand
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Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function
Optogenetic methods have emerged as powerful tools for dissecting neural circuit connectivity, function and dysfunction. We used a bacterial artificial chromosome (BAC) transgenic strategy to expressExpand
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Sim-to-Real: Learning Agile Locomotion For Quadruped Robots
A system to learn quadruped locomotion from scratch using deep reinforcement learning using simple reward signals. Expand
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Remodeling of cardiac fiber structure after infarction in rats quantified with diffusion tensor MRI.
Structural remodeling of myocardium after infarction plays a critical role in functional adaptation. Diffusion tensor magnetic resonance imaging (DTMRI) provides a means for rapid and nondestructiveExpand
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Unsupervised Feature Construction and Knowledge Extraction from Genome-Wide Assays of Breast Cancer with Denoising Autoencoders
We present denoising autoencoders (DAs), which employ a data-defined learning objective independent of known biology, as a method to identify and extract complex patterns from genomic data. Expand
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Mediation of Epstein–Barr virus EBNA‐LP transcriptional coactivation by Sp100
The Epstein–Barr virus (EBV) EBNA‐LP protein is important for EBV‐mediated B‐cell immortalization and is a potent gene‐specific coactivator of the viral transcriptional activator, EBNA2. TheExpand
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Detection of pathogenic elephant endotheliotropic herpesvirus in routine trunk washes from healthy adult Asian elephants (Elephas maximus) by use of a real-time quantitative polymerase chain reaction
OBJECTIVE To investigate the pathogenesis and transmission of elephant endotheliotropic herpesvirus (EEHV1) by analyzing various elephant fluid samples with a novel EEHV1-specific real-time PCRExpand
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Murine Gammaherpesvirus 68 Open Reading Frame 75c Tegument Protein Induces the Degradation of PML and Is Essential for Production of Infectious Virus
ABSTRACT Promyelocytic Leukemia nuclear body (PML NB) proteins mediate an intrinsic cellular host defense response against virus infections. Herpesviruses express proteins that modulate PML orExpand
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Learning to Walk via Deep Reinforcement Learning
We propose a sample-efficient deep RL algorithm based on maximum entropy RL that requires minimal per-task tuning and only a modest number of trials to learn neural network policies. Expand
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Bacterial Community Composition in the Gut Content and Ambient Sediment of Sea Cucumber Apostichopus japonicus Revealed by 16S rRNA Gene Pyrosequencing
The composition of the bacterial communities in the contents of the foregut and hindgut of the sea cucumber Apostichopus japonicus and in the ambient surface sediment was surveyed by 16S rRNA geneExpand
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