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Micellar Solubilization of Timobesone Acetate in Aqueous and Aqueous Propylene Glycol Solutions of Nonionic Surfactants
The micellar solubilization of timobesone acetate, a novel topical corticosteroid, was studied in aqueous and aqueous propylene glycol solutions of 1 to 5% nonionic surfactants at 25°C. The… Expand
Drug-excipient interactions resulting from powder mixing. VI: Role of various surfactants
Abstract The role of various surfactants on the drug-excipient interactions resulting from prolonged powder mixing with magnesium stearate was investigated. Drug-excipient formulations containing… Expand
Intrinsic potencies of novel thiol ester corticosteroids RS-85095 and RS-21314 as compared with clobetasol 17-propionate and fluocinonide.
- J. T. Ong, B. Poulsen, W. Akers, J. R. Scholtz, F. Genter, D. Kertesz
- Archives of dermatology
- 1 December 1989
The intrinsic potencies of two novel topical thiol ester corticosteroids, RS-85095 and RS-21314, were compared with the high potency corticosteroids clobetasol 17-propionate and fluocinonide, using… Expand
Formation of N-nitrosodiethanolamine from the peroxidation of diethanolamine
Release of Lonapalene from Two-Phase Emulsion-Type Ointment Systems
The in vitro release of lonapalene, a novel nonsteroidal antipsoriatic agent, was studied from two-phase emulsion-type ointment systems into a perfect sink of propylene carbonate at 32°C. Lonapalene… Expand