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Stride length regulation in Parkinson's disease. Normalization strategies and underlying mechanisms.
Results of our previous studies have shown that the slow, shuffling gait of Parkinson's disease patients is due to an inability to generate appropriate stride length and that cadence control isExpand
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The pathogenesis of gait hypokinesia in Parkinson's disease.
To identify the fundamental deficit in gait hypokinesia in Parkinson's disease (PD) we conducted a series of experiments that compared PD subjects with age- and height-matched controls in theirExpand
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Hand Coordination in Bimanual Circle Drawing
Two right-handed and 2 left-handed participants drew circles in the horizontal plane with both hands simultaneously in either a symmetrical or an asymmetrical mode, at their preferred rate or as fastExpand
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Ability to modulate walking cadence remains intact in Parkinson's disease.
Gait hypokinesia (slowness) is a characteristic feature of Parkinson's disease. It is not clear, however, whether the slowness is due to a problem in regulation of the timing of consecutive steps orExpand
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Abnormalities in the stride length-cadence relation in parkinsonian gait.
The purpose of this investigation was to clarify abnormalities in the stride length-cadence relation in gait hypokinesia in Parkinson's disease (PD). A second aim was to investigate the effect ofExpand
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Delayed plastic responses to anodal tDCS in older adults
Despite the abundance of research reporting the neurophysiological and behavioral effects of transcranial direct current stimulation (tDCS) in healthy young adults and clinical populations, theExpand
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Absence of cross-limb transfer of performance gains following ballistic motor practice in older adults.
The phenomenon of cross-limb transfer, in which unilateral strength training can result in bilateral strength gains, has recently been tested for ballistic movements. Performance gains associatedExpand
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Bilateral movement training and stroke rehabilitation: A systematic review and meta-analysis
OBJECTIVE AND DESIGN Bilateral movement training is being increasingly used as a post-stroke motor rehabilitation protocol. The contemporary emphasis on evidence-based medicine warrants a prospectiveExpand
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Inter- and Intra-individual Variability Following Intermittent Theta Burst Stimulation: Implications for Rehabilitation and Recovery
BACKGROUND The continued refinement of non-invasive brain stimulation (NBS) techniques is indicative of promising clinical and rehabilitative interventions that are able to modulate corticalExpand
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Age-related differences in corticospinal excitability and inhibition during coordination of upper and lower limbs
The ability to coordinate upper and lower limbs--a prerequisite for many everyday activities--is known to decline with age. Here we report 2 experiments in which transcranial magnetic stimulationExpand
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