J. Su

Publications259
h-index32
Citations3,887
Highly Influential Citations62
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New β-Caryophyllene-Derived Terpenoids from the Soft Coral Sinularia nanolobata
TLDR
The cytotoxicity of 1−6 against the growth of a limited panel of cancer cell lines is described and the structures of 1+5 were elucidated on the basis of extensive spectroscopic analyses and by comparison of the spectral data with those of the related metabolites.
Steroid and cembranoids from the Dongsha atoll soft coral Lobophytum sarcophytoides
Meroditerpenoids from a Formosan soft coral Nephthea chabrolii.
TLDR
Eight new meroditerpenoid-related metabolites, including one naphthoquinone derivative, chabrolonaphthOquinone B, and four tetraprenyltoluquinone-related compounds, chABrolobenzoquinones E-H, were isolated from the organic extract of a Taiwanese soft coral Nephthea chabroii.
Structural Elucidation and Structure-Anti-inflammatory Activity Relationships of Cembranoids from Cultured Soft Corals Sinularia sandensis and Sinularia flexibilis.
TLDR
Structural-activity relationship analysis indicated that cembrane-type compounds with one seven-membered lactone moiety at C-1 are potential anti-inflammatory agents.
Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells
TLDR
This study reveals for the first time the anti-HCC activities of sinularin, the active compound isolated from the cultured soft coral Sinularia flexibilis.
11-epi-Sinulariolide Acetate Reduces Cell Migration and Invasion of Human Hepatocellular Carcinoma by Reducing the Activation of ERK1/2, p38MAPK and FAK/PI3K/AKT/mTOR Signaling Pathways
TLDR
It is discovered that 11-epi-SA provided a concentration-dependent inhibitory effect on the migration of human HCC HA22T cells, and suppressed the phosphorylation of ERK1/2 and p38MAPK pathways.
A Soft Coral-Derived Compound, 11-epi-Sinulariolide Acetate Suppresses Inflammatory Response and Bone Destruction in Adjuvant-Induced Arthritis
TLDR
Based on its attenuation of the expression of proinflammatory proteins and disease progression in AIA rats, the marine-derived compound Ya-s11 may serve as a useful therapeutic agent for the treatment of RA.
Oxygenated cembranoids from a Formosan soft coral Sinularia gibberosa.
TLDR
Chemical investigation of a Formosan soft coral, Sinularia gibberosa, has led to the isolation of eight oxygenated cembranoids, including seven new compounds, gibberosenes A-G, which were found to be cytotoxic toward a limited panel of cancer cell lines.
Bioactive new withanolides from the cultured soft coral Sinularia brassica.
Towards the Small and the Beautiful: A Small Dibromotyrosine Derivative from Pseudoceratina sp. Sponge Exhibits Potent Apoptotic Effect through Targeting IKK/NFκB Signaling Pathway
TLDR
The results of a set of experiments designed to reveal the underlying mechanism of DT cytotoxic activity against K562 cells suggested that DT can act as a topoisomerase II catalytic inhibitor, unlike the clinical anticancer drug, etoposide, which acts as aTopoisomersase poison.
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