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Steroid and cembranoids from the Dongsha atoll soft coral Lobophytum sarcophytoides
A novel sterol, sarcophytosterol ( 1 ), and four new cembranoids, sarcophytolins A–D ( 2 – 5 ), have been isolated from the soft coral Lobophytum sarcophytoides along with four known metabolites 6 –… Expand
New β-Caryophyllene-Derived Terpenoids from the Soft Coral Sinularia nanolobata
Two new norsesquiterpenoids, nanonorcaryophyllenes A (1) and B (2), two new diterpenoids, nanolobatins A (3) and B (4), and a novel norditerpenoid, nanolobatin C (5), were isolated from the n-hexane… Expand
Towards the Small and the Beautiful: A Small Dibromotyrosine Derivative from Pseudoceratina sp. Sponge Exhibits Potent Apoptotic Effect through Targeting IKK/NFκB Signaling Pathway
A dibromotyrosine derivative, (1′R,5′S,6′S)-2-(3′,5′-dibromo-1′,6′-dihydroxy-4′-oxocyclohex-2′-enyl) acetonitrile (DT), was isolated from the sponge Pseudoceratina sp., and was found to exhibit a… Expand
Oxygenated cembranoids from a Formosan soft coral Sinularia gibberosa.
Chemical investigation of a Formosan soft coral, Sinularia gibberosa, has led to the isolation of eight oxygenated cembranoids, 1- 8, including seven new compounds, gibberosenes A-G ( 2- 8). None of… Expand
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway
- Tsung-Chang Tsai, Kuei-Hung Lai, J. Su, Yu-Jen Wu, J. Sheu
- Chemistry, Medicine
- Marine drugs
- 26 March 2018
The 7-Acetylsinumaximol B (7-AB), a bioactive cembranoid, was originally discovered from aquaculture soft coral Sinularia sandensis. The current study investigated the anti-proliferative property of… Expand
Meroditerpenoids from a Formosan soft coral Nephthea chabrolii.
- J. Su, A. F. Ahmed, P. Sung, Y. Wu, J. Sheu
- Medicine, Biology
- Journal of natural products
- 1 November 2005
Eight new meroditerpenoid-related metabolites, including one naphthoquinone derivative, chabrolonaphthoquinone B (1), four tetraprenyltoluquinone-related compounds, chabrolobenzoquinones E-H (2-5),… Expand
Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway
Sinulariolide, an active compound isolated from the cultured soft coral Sinularia flexibilis, has potent anti-microbial and anti-tumorigenesis effects towards melanoma and bladder cancer cells. In… Expand
Anti-inflammatory cembranoids from the soft corals Sinularia querciformis and Sinularia granosa.
Four new cembranoids, querciformolides A-D (1-4), along with two known cembranoids, 7 and 8, have been isolated from the soft coral Sinularia querciformis. Furthermore, chemical investigation of… Expand
Manaarenolides A-I, diterpenoids from the soft coral Sinularia manaarensis.
- J. Su, A. F. Ahmed, P. Sung, Chih-Hua Chao, Y. Kuo, J. Sheu
- Biology, Medicine
- Journal of natural products
- 1 August 2006
Nine cembrane-type diterpenoids, manaarenolides A-I (1-9), along with two known cembranolides, 10 and 11, have been isolated from the ethyl acetate extract of the Taiwanese soft coral Sinularia… Expand
Scabrolides E-G, three new norditerpenoids from the soft coral Sinularia scabra.
Three new norditerpenoids, scabrolides E-G (1-3), and dissectolide A (4) have been isolated from the organic extract of a Taiwanese soft coral Sinularia scabra. The structures of 1-3 were determined… Expand